dioxygenases

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dioxygenases

enzymes which incorporate both atoms of O2 into one substrate. Less common than mono-oxygenases. Important example is the 15-15′-dioxygenase enzyme in the small intestine which cleaves plant carotenoids containing provitamin A activity, such as β-carotene, into retinal. This enzyme is absent from felines, such as the cat, and is the reason cats are dependent on animal sources of vitamin A.
References in periodicals archive ?
The catabolism of phenanthrene by bacteria has been extensively studied, and, in general, phenanthrene is metabolized by initial dioxygenation at the 3,4-position.
Arene hydroxylases: metalloenzymes catalyzing dioxygenation of aromatic compounds.