dioxygenases

(redirected from Dioxygenation)

dioxygenases

enzymes which incorporate both atoms of O2 into one substrate. Less common than mono-oxygenases. Important example is the 15-15′-dioxygenase enzyme in the small intestine which cleaves plant carotenoids containing provitamin A activity, such as β-carotene, into retinal. This enzyme is absent from felines, such as the cat, and is the reason cats are dependent on animal sources of vitamin A.
References in periodicals archive ?
2009) Cytoglobin is expressed in the vasculature and regulates cell respiration and proliferation via nitric oxide dioxygenation.
The catabolism of phenanthrene by bacteria has been extensively studied, and, in general, phenanthrene is metabolized by initial dioxygenation at the 3,4-position.
Arene hydroxylases: metalloenzymes catalyzing dioxygenation of aromatic compounds.