DMSO

(redirected from Dimethyl sulphoxide)
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Related to Dimethyl sulphoxide: Dimethyl sulfide, Dimethyl sulfate

DMSO

 
dimethyl sulfoxide, an industrial solvent that has the ability to penetrate plant and animal tissues and to preserve living cells during freezing. It has been used investigationally as an agent to increase the penetrability of other substances and as a topical analgesic and antiinflammatory. It has been approved by the U.S. Food and Drug Administration in a 50 per cent solution for direct instillation into the bladder for the treatment of interstitial cystitis. A 90 per cent solution, which has been approved only for veterinary use, is believed by some to be beneficial in the treatment of muscle sprains and strains, arthritis, spinal cord injuries, and the aftereffects of stroke when it is applied externally and absorbed by the skin. Claims that it is effective for treating these disorders in humans have not been validated by research studies. It has been shown to produce some short-term side effects.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

DMSO

Abbreviation for dimethyl sulfoxide.
Farlex Partner Medical Dictionary © Farlex 2012

DMSO

(dē′ĕm-ĕs-ō′)
n.
A colorless hygroscopic liquid, (CH3)2SO, obtained from lignin, used as an industrial solvent and in medicine as a penetrant to convey medications into the tissues.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

DMSO

Alternative medicine
A substance that occurs naturally in minute amounts in certain foods, which has industrial and health-related applications. Animal studies have shown it to have analgesic, anti-inflammatory, antimicrobial, vasodilatory and other properties; up to the 1960s, DMSO had been administered orally, topically or parenterally by mainstream physicians for various conditions, including arthritis, bursitis, cancer, emphysema, mental illness and pain. In the face of its association with lenticular degeneration, DMSO was removed from general use; some practitioners of alternative healthcare continue to recommend DMSO for these and other uses.
 
Toxicity
Topical DMSO is associated burning, itching and an unpleasant odour.
 
Mainstream medicine
DMSO is FDA-approved for treating interstitial cystitis, and may be of use in treating scleroderma, sprains, arthritis, cerebrovascular accidents, familial amyloidotic polyneuropathy and acetaminophen hepatotoxicity. DMSO reduces the ice crystals formed in frozen section tissues from the operating suite, and may be an effective cryopreservative.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

DMSO

Abbreviation for dimethyl sulfoxide.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

DMSO

Abbreviation for dimethyl sulfoxide.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Concerning the impact of dimethyl sulphoxide, the addition of DMSO seems to be the most critical point regarding the loss of viability with an impact stronger than that of the delay between parturition and processing.
Tolerance of [CD34.sup.+] cells to multimolar dimethyl sulphoxide and the effect of cooling rate on recovery after freezing and thawing," Cryobiology, vol.
The modulation of membrane structure and stability by dimethyl sulphoxide (review).
We evaluated 5 CPA combinations at each of three concentrations: (1) 1 M trehalose and 5, 10 and 15% dimethyl sulphoxide (DMSO); (2) Hanks Calcium-free Balanced Salt Solution (C-F HBSS) (Paniagua-Chavez et al.
Oral dimethyl sulphoxide, etretinate and penicillamine are also beneficial.
Petroleum ether, ethyl acetate, dimethyl sulphoxide, carbon dioxide, methanol, acetic acid, disodium hydrogen phosphate, monosodium dihydrogen phosphate, Wright's giemsa stain, silica gel (60-120), Tris-HCl, ethylenediaminetetracetic acid (EDTA), sodium chloride (NaCl), sodium dodecylsulphate (SDS), ammonium acetate was purchased from Sisco Research Laboratory Pvt.
Compounds were freshly prepared by dissolving in dimethyl sulphoxide (1g/1ml) and diluted with RPMI-1640 media.
After removing bark, 10 mg of wet lichen thallus of each specimen was crushed and suspended in a 10 ml screw cap bottle containing 5 ml of 10% dimethyl sulphoxide in distilled water (DMSO/DW) and kept in the freezer at 4 [degrees]C for 48 hours.
Seventy seven species of the family Graphidaceae were extracted with aqueous solution of methanol containing dimethyl sulphoxide. Out of seventy seven, 30 species gave extract yields in the range of 7-77.5 [micro]g and were found to show both superoxide scavenging activity (SSA) and inhibition of xanthine oxidase (IXO) activities (Table 1).
2 ml of this suspension was incubated with various concentrations of the test material dissolved in Dimethyl sulphoxide (DMSO) and incubated at 18-20 [degrees]C in the dark.