dimer

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Related to Dimerizes: Heterodimeric, Dimerisation

dimer

 
1. a compound formed by combination of two identical simpler molecules.
2. a capsomer having two structural subunits.
D-dimer a fragment of fibrin that is formed as a result of fibrin degradation. A positive test for its presence in the blood is suggestive of conditions such as thrombotic disease, sickle cell crisis, malignancy, disseminated intravascular coagulation, or recent surgery.

di·mer

(dī'mĕr),
A compound or unit produced by the combination of two like molecules; in the strictest sense, this occurs without the loss of atoms (thus, nitrogen tetroxide, N2O4, is the dimer of nitrogen dioxide, NO2), but usually by elimination of H2O or a similar small molecule between the two (for example, a disaccharide), or by simple noncovalent association (as of two identical protein molecules); higher orders of complexity are called trimers, tetramers, oligomers, and polymers.
[G. di-, two, + -mer]

di·mer

(dī'mĕr)
A compound or unit produced by the combination of two like molecules; in the strictest sense, without loss of atoms (thus nitrogen tetroxide, N2O4, is the dimer of nitrogen dioxide, NO2), but usually by elimination of H2O or a similar small molecule between the two (e.g., a disaccharide), or by simple noncovalent association (as of two identical protein molecules); higher orders of complexity are called trimers, tetramers, oligomers, and polymers.
[G. di-, two, + -mer]

dimer

a molecule made by the joining of two molecules of the same kind, i.e. two MONOMERS. Ultraviolet light can induce THYMINE DIMERS in DNA.
References in periodicals archive ?
However, this strategy restricts the overall targetable sequence space because it requires two Cas9-compatible sequences to be close enough (~15 to 25 bp) in order for FokI to dimerize and cleave the target DNA.
Because dialkylsilylene 31 is sterically well protected and does not dimerize to the corresponding disilene either in solution or in the solid state, tethering two dialkylsilylene moieties may be possible to give a stable tethered bissilylene.
Under hypoxic condition, this constitutive decay of HIF-1[alpha] is suppressed, allowing it to translocate into the nucleus where it dimerizes with ARNT (6).
For the methyl acetate system, acetic acid dimerizes in the vapour phase.
Under hypoxia conditions, the prolyl hydroxylase (PHD) becomes nonfunctional and the stabilized HIF-1[alpha] could translocate into the nucleus and dimerizes with the HIF-1[beta] subunit.
STAT3 is phosphorylated by Janus family kinase (JAK) at [Tyr.sup.705] and dimerizes and translocates to the nucleus to regulate gene expression [19].
Following activation,[sup][10] the monomeric EGFR dimerizes, which further activates the intracellular kinase pathways and causes auto-phosphorylation of tyrosine to residue.
After activation, NR1I3 translocates to the nucleus and dimerizes with NR2B1 (retinoid X-receptor alpha, RXR-alpha); the resulting heterodimer recognizes NR1I3-responsive elements through the genome, thus regulating expression of several genes (1).
It is known that dioxins and dioxin-like compounds, TCDD, PAH, and particulate matter (PM), can activate AhR, which then translocates to the nucleus and dimerizes with AhR nuclear translocator (ARNT).
After AhR binds to its ligand, the above-mentioned complex disintegrates, ligand-bound AhR moves to the nucleus, and dimerizes with Arnt (aryl hydrocarbon receptor nuclear translocator).
CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.
It dimerizes with a protein called Max, to bind Enhancer Box sequences (E-boxes) and recruits view of the above findings it was important to determine the role of CDK2.