Relatively low risk: Parkinson's disease medications such as levodopa/carbidopa (Parcopa, Sinemet) and amantadine; antihypertensive drugs such as Clonidine hydrochloride (Catapres); calcium channel blockers, such as diltiazem (including Cardizem and Dilacor
), and verapamil (Calan); beta-blockers, such as atenolol (Tenormin), propanolol (Inderal) and timolol (Timoptic); the Alzheimer's disease drug donepezil (Aricept); hormone replacement drugs, such as estrogen (Enjuvia, Cenextin, etc.), medroxyprogesterone (Provera) and conjugated estrogens/medroxyprogesterone (Prempro); and benzodiazepines, such as diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan) and estazolam (ProSom).
Drugs that can cause this interaction include some AIDS, medications, the antibiotics erythromycin (ERY-C), clarithromycin (Biaxin), the calcium-channel blocker diltiazem (Cardizem, Dilacor
), and the heart medication verapamil (Calan, Isoptin).
propranolol HCI (Inderal) Calcium Channel Blockers: Help to regulate heart rate, diltiazem (Cardizem, Dilacor
XR, Diltia relax blood vessels.
(Norvasc) Cardizem CD/SR, Diltiazem HCl Hoechst Marion Rous- Dilacor
XR, Tiazac, sel (Cardizem), Diltlazem HCl Rhone-Poulenc Rorer Pharmaceuticals Inc.
dosage, the generic equivalent of Watson Laboratories Inc.'s heart medication Dilacor
XR capsules; ticlopidine HCl tablets, 250 mg., the generic equivalent of Roche Laboratories Inc.'s Ticlid tablets for stroke patients; 400 mg.
These products, and those under FDA review including Procardia XL and Dilacor
XR, will contribute to our future growth.
Watson also seeks damages from Rhone-Poulenc for breach of contract and unfair competition arising, in part, from Rhone-Poulenc 's failure to fulfill its supply obligations to Watson for Dilacor
XR branded product and its generic equivalent.
The company intends to introduce its cost-effective versions into the marketplace when it is practicable, as it did in June 1999 and October 1997, when Andrx began selling bioequivalent versions of Cardizem CD and Dilacor
diltaizem (Cardizem, Dilacor
XR, Lower blood pressure.
"Finally, those purporting to look for "conspiracies" ignore the fact that Andrx was the first company to receive FDA approval for a bioequivalent version of Dilacor
XR, which we immediately made available to the consumer.
And last fall Andrx launched Diltia XT, a generic version of Dilacor
XR, a blood pressure drug from Rhone-Poulenc Rorer Pharmaceuticals Inc.
are two other generics firms that now have interest in the branded side: Teva with its multiple sclerosis treatment Copaxone; and Watson with it hypertension treatment Dilacor
and the oral contraceptive Zovia.