Fukushima, "Enhancing effects of diallyl sulfide
on hepatocarcinogenesis and inhibitory actions of the related diallyl disulfide on colon and renal carcinogenesis in rats," Carcinogenesis, vol.
Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats.
Diallyl sulfide. diallyl disulfide, and diallyl trisulfide inhibit migration and invasion in human colon cancer cold 205 cells through the inhibition of matrix metalloproteinase-2, -7, and -9 expressions.
Diallyl sulfide, a flavor component of garlic (Allium sativum), inhibits dimethylhydrazine-induced colon cancer.
Chemoprevention of N-nitrosomethylbenzylamine-induced esophageal cancer in rats by the naturally occurring thioether, diallyl sulfide. Cancer Res 48:6872-6875 (1988).
Chin et al., "The effects of diallyl sulfide upon Porphyromonas gingivalis lipopolysaccharide stimulated proinflammatory cytokine expressions and nuclear factor-kappa B activation in human gingival fibroblasts," Journal of Periodontal Research, vol.
Pistelli, "The role of diallyl sulfides and dipropyl sulfides in the in vitro antimicrobial activity of the essential oil of garlic, Allium sativum L., and leek, Allium porrum L.," Phytotherapy Research, vol.
Two previous works published last year by Lu and WSU colleagues in Applied and Environmental Microbiology and Analytical Chemistry found diallyl sulfide and other organosulfur compounds effectively kill important foodborne pathogens, such as Listeria monocytogenes and Escherichia coli O157:H7.
However, "diallyl sulfide may be useful in reducing the levels of the Campylobacter in the environment and to clean industrial food processing equipment, as the bacterium is found in a biofilm in both settings," Konkel added.
Wargovich speculates that large quantities of diallyl sulfide
could help the liver detoxify the carcinogen.
We compared the activities of the volatile oils of Allium species with allicin and with diallyl sulfide
and allyl sulfide, which are the expected decomposition products of allicin.
The composition (per 100 mg) obtained by gas chromatography was as follows: diallyl sulfides
1.2%, allylmethyl sulfide 4.2%, diallyl disulfide 21.5%, allylmethyl trisulfide 8.8%, diallyl tetrasulfide 5.0%, and 3-vinyl-l,2-dithiin 5.3%, among other components.