Despite the high specificities of these assays, their main disadvantages include a rather small diagnostic window
for detection and, for NS1 antigen capture tests, low sensitivities during secondary DENV infections (5).
Disadvantages: Small diagnostic window
, a single diagnostic parameter and service required usually at peak time in the breeding season.
Steiner said that he would like to see changes to the diagnostic criteria for postpartum depression, and that the DSM-5 should extend the diagnostic window
for its onset to 6 months post partum.
Characterisation of the diagnostic window
of serum glial fibrillary acidic protein for the differentiation of intracerebral haemorrhage and ischaemic stroke.
The fourth generation uses the simultaneous detection of HIV-1 p24 antigen and antibodies to HIV-1 and HIV-2 to allow an even earlier diagnosis (reducing the diagnostic window
by four days in average compared with third generation) and to include a broader range of strains.
The diagnostic window
: Culture and gender-sensitive diagnosis and training.
Most importantly, CK decreased from peak concentrations faster than both cTnI and cTnT, indicating a narrower diagnostic window
. The return to basal values of cardiac troponins and CK was delayed by repeat dosing, but was not inhibited.
(a) Patients with cTnT 0.1 [greater than or equal to]g/ 5/9 (55.6) L on admisssion, n (%) Patients positive at 4 h, n (%) 7/9 (77.8) Patients positive at 8 h, n (%) 9/9 (100) Sampling period, h 40 (25-76) Peak cTnT, [micro]g/L 0.48 (0.24-0.66) Time to peak, h 10 (8-15) Diagnostic window
based on 0.1 [micro]g/L cutoff, h 30 (27-39) Diagnostic window
based on 0.03 [micro]g/L, h 35 (30-52) Time of detectable cTnT (>0.01 [micro]g/L), h 40 (35-60) (1) Data given as medians with interquartile ranges (25th-75th percentiles) or as absolute numbers with relative frequencies.
Thus, the diagnostic window
was narrower than it is during acute myocardial infarction, probably because of the lower peak serum concentration of cTnI.
The system also reports critical vessel parameters via indicator limps for each function and reports failure conditions through self diagnostics displayed on Caterpillar's Marine Power Display diagnostic windows
or the Cat Electronic Technician system.