USP8
(redirected from Deubiquitinating enzyme 8)USP8
A gene on chromosome 15q21.2 that encodes an enzyme which deubiquitinates target proteins (e.g., BIRC6, KIF23, STAM2, RASGRF1, ESCRT-0, EGFR, EPS15, RASGRF1, RNF41, YWHAE, YWHAG and YWHAZ), preventing their degradation and thus playing an important regulatory role in protein turnover.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.