(The ring uses a related compound.) These pills (brands such as Desogen
, Mircette, and Cyclessa) were developed in the 1980s to lessen the pill's minor side effects, like acne and facial hair.
It obtained the drug, which is AB-rated to Desogen
(desogestrel and ethinyl estradiol), through a generic supply agreement with Organon Ireland Ltd.
The third-generation progestins--norgestimate (OrthoCyclen, Ortho Tri-Cyclen) and desogestrel (Desogen
, OrthoCept, Mircette)--are less likely to cross-react with androgen receptors.
The product is a generic oral contraceptive to the AB-rated brands Desogen
and Ortho-Cept (Organon USA Inc.
Johnson Pharmaceutical's Ortho-Cept and Organon Pharmaceutical's Desogen
. Annual combined brand revenue for the two was about $155 million last year.
The FDA has determined it to be a substitutable equivalent oral contraceptive for Ortho-Cept and Desogen
tablets, which are marketed by Ortho-McNeil Pharmaceutical and Organon Inc., respectively.