desmosome

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des·mo·some

(dez'mō-sōm),
A site of adhesion between two epithelial cells consisting, in each cell, of a dense attachment plaque with associated intermediate filaments and transmembrane proteins known as cadherins.
[desmo- + G. sōma, body]
Farlex Partner Medical Dictionary © Farlex 2012

des·mo·some

(des'mō-sōm)
A site of adhesion between two epithelial cells, consisting of a dense attachment plaque separated from a similar structure in the other cell by a thin layer of extracellular material.
Synonym(s): macula adherens.
[desmo- + G. sōma, body]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

desmosome

a thickened zone in the cell membrane of adjacent eukaryote cells.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

desmosome

A site of adhesion between two adjacent cells, such as in the corneal epithelium. It consists of a small, dense body in which the two halves are separated by an intercellular gap filled with extracellular substance. The basal cells are attached at irregular intervals to the underlying basement membrane (adjacent to Bowman's layer) by hemidesmosomes (one half of a desmosome). Thus, scraping off the epithelium usually leaves fragments of the basal cells attached to the basement membrane.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann
References in periodicals archive ?
In cell lines without DP-NTP, plakoglobin codistributed diffusely along the membrane with desmosomal cadherins. But in cells coexpressing DP-NTP, desmosomal cadherins and plakoglobin were redistributed into punctate structures containing DP-NTP.
Transfection of desmosomal cadherins leads to stabilization of this endogenous plakoglobin.
Several laboratories have mapped plakoglobin binding sites for classic and desmosomal cadherins.
The plakoglobin binding site for desmosomal cadherins appears to be at the ends of the plakoglobin armadillo repeats, whereas classic cadherins bind to the more central armadillo repeats.
QUESTION: Is the actin-mediated adherens junction disrupted by the presence of desmosomal cadherins that shouldn't be able to link up?