desferrioxamine

desferrioxamine

/des·fer·ri·ox·amine/ (des-fer´e-oks´ah-mēn) deferoxamine.

desferrioxamine

An iron CHELATING AGENT used in iron overload conditions or iron poisoning. A brand name is Desferal.

desferrioxamine

see deferoxamine.

deferoxamine, desferrioxamine

an iron chelating compound used as the mesylate to treat iron poisoning.
References in periodicals archive ?
This dopaminergic neuroprotection was proved in animal models, wherein the iron chelator desferrioxamine ameliorated iron accumulation.
Growth failure and bone lesions due to desferrioxamine in thalassaemic patients.
The effects of ROS were characterized using specific inhibitors, including 250 [micro]M of hydralazine and 1 mM of desferrioxamine as inhibitors of peroxynitrite ([ONOO.
Serum ferritin levels, socio-demographic factors and desferrioxamine therapy in multi-transfused thalassemia major patients at a government tertiary care hospital of Karachi, Pakistan.
Possible protective effect of melatonin and/or desferrioxamine against streptozotocin-induced hyperglycaemia in mice.
Ascorbic acid enhancement of desferrioxamine induced urinary iron excretion in Thallassemia patients.
A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in beta-thalassemia major patients receiving desferrioxamine.
Desferrioxamine (DFO) used in numerous in vivo and in vitro investigations has also been used clinical trials.
Fourteen (56%) patients were on oral deferiprone, 4 (16%) on desferrioxamine and 2 (8%) were on the new oral chelator deferasirox and 5 (20%) patients were on combined chelation therapy of deferiprone and desferrioxamine.
All patients had been diagnosed with either [beta]-thalassemia major (BTM) or [beta]-thalassemia intermedia (BTI), and all had received at least 1 year of treatment within the previous year with an iron chelator--either deferasirox, desferrioxamine (deferoxamine in the United States), deferiprone, or a combination of desferrioxamine and deferiprone.