Desferoxamine

Desferoxamine

The primary drug used in iron chelation therapy. It aids in counteracting the life-threatening buildup of iron in the body associated with long-term blood transfusions.
Mentioned in: Thalassemia
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Some of the other agents causing urinary discoloration are Myoglobin, haemoglobin, porphyrins from endogenous sources whereas Rhubarb, black, berries, beet root, artificial food colors and medicines like Rifampin, desferoxamine, Phenolphthalein, Phen-azopyridine etc.
Desferoxamine (DFO)-mediated iron chelation: rationale for a novel approach to therapy for brain cancer.
Cobalt (II) chloride (Co[Cl.sub.2]), desferoxamine (DFO), dimethyloxalylglycine (DMOG), okadaic acid (OA), and glutathione (GSH) were provided by Sigma-Aldrich, USA.
To control the iron levels in their bodies and protect their hearts, doctors at Philippine Children's Medical Center have placed the children on medication: Desferoxamine and Defereprone for both of them and Sumapen for Daisy.
Besides, the proposed scaffold has gradient changing construct, so a vertical gradient porosity along the thickness can be obtained which make it possible to realize spatially control release of desferoxamine (DFO).
The effect of desferoxamine and ferrostatin-1 on the cytotoxicity of artenimol of CCRF-CEM cells was determined by resazurin assays.
(30) Paul Cutler found significant improvement in diabetic control with the use of the iron chelator, desferoxamine, in diabetic patients who also had high ferritin levels.
Conditions predisposing to these infections include diabetes mellitus, hematologic malignancies, organ transplantation, steroid use, acquired immunodeficiency syndrome, treatment with desferoxamine, and iron overload.
Ludolph et al., "Desferoxamine and ethyl-3,4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS," American Journal of Physiology - Heart and Circulatory Physiology, vol.
The effects of desferoxamine and ascorbate on oxidative stress in the streptozotocin diabetic rat.
The only drug currently available for the clinical treatment of aluminum intoxication is a natural siderophore desferoxamine B (Hider et al., 1991).