Fatty acid desaturase
2 (fads2), a gene related to dyslipidemia, primarily participates in metabolism of unsaturated fatty acids, affecting the concentrations of total cholesterol, low density lipoprotein cholesterol, high lipoprotein cholesterol, and triglyceride .
In the present study, Nicotiana benthamiana Phytoene Desaturase
(NbPDS) gene was targeted by CRISPR/Cas9 system.
The fat-1 transgenic mouse was genetically modified to express a fat-1 gene that encodes n-3 PUFA desaturase
Environmental stress has a profound effect on fatty acid desaturase
activity and fatty acid composition, which function as key factors in plant survival under stressful conditions.
(3) [[DELTA].sup.9]- Dessat (18) - index of desaturase
enzyme activity C18 = 100(18:1/18:0+18:1).
Ntambi, "Stearoyl-CoA desaturase
and its relation to high-carbohydrate diets and obesity," Biochimica et Biophysica Acta, vol.
Fatty acid synthase, hormone sensitive lipase, lipoprotein lipase, adipose triacylglycerol lipase, acyl-CoA, diacylglycerol acyltransferase 2, elongase of very long-chain fatty acid 6, and [DELTA]5 and [DELTA]6 fatty acid desaturase
activity was detected and showed a negative trend with an increase of salinity, and no significant differences were found among salinity groups (P > 0.05).
The increase of SFA at the expense of MUFA most likely resulted from the inhibition of the A-9 desaturase
enzyme system that is responsible for SFA desaturation, converting SFA into MUFA .
Indeed, the chronic treatment with risperidone or paliperidone induced liver enzymes such as fatty acid desaturase
The selected genes include four encoding signaling proteins (FGFR3 encoding fibroblast growth factor receptor 3, EPHB2 encoding ephrin type-B receptor 2, GREM1 encoding gremlin 1, and IGFBP2 encoding insulin-like growth factor binding protein 2), two extracellular matrix genes (COL3A1 encoding collagen, type III, alpha 1, and TNC encoding cytotactin or tenascin-C), and two metabolic genes (ACBD7 encoding acyl-CoA-binding domain containing 7 and SCD encoding stearoyl-CoA desaturase
The top down-regulated genes were Major urinary protein 4 (Mup4), Major urinary protein 2 (Mup2), Carbonic anhydrase III (Ca3), Adiponectin (Adipoq), TATA box binding protein (Tbp), Stearoyl-CoA desaturase
1 (Scd1), ELOVL family member 5, elongation of long chain fatty acids (ElvolS), and tubulin (Tubg2) (Table 4).
In those studies, sterculic oil was found to suppress the bodily enzyme stearoyl-CoA desaturase