desaturase


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desaturase

(dē-sach′ŭ-rās″) [ de- + satur(ate) + -ase]
An enzyme that converts an unsaturated fatty acid chain to one that includes at least one carbon-carbon double bond.
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References in periodicals archive ?
Fatty acid desaturase 2 (fads2), a gene related to dyslipidemia, primarily participates in metabolism of unsaturated fatty acids, affecting the concentrations of total cholesterol, low density lipoprotein cholesterol, high lipoprotein cholesterol, and triglyceride [18].
In the present study, Nicotiana benthamiana Phytoene Desaturase (NbPDS) gene was targeted by CRISPR/Cas9 system.
The fat-1 transgenic mouse was genetically modified to express a fat-1 gene that encodes n-3 PUFA desaturase [15, 16].
Environmental stress has a profound effect on fatty acid desaturase activity and fatty acid composition, which function as key factors in plant survival under stressful conditions.
Ntambi, "Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity," Biochimica et Biophysica Acta, vol.
Fatty acid synthase, hormone sensitive lipase, lipoprotein lipase, adipose triacylglycerol lipase, acyl-CoA, diacylglycerol acyltransferase 2, elongase of very long-chain fatty acid 6, and [DELTA]5 and [DELTA]6 fatty acid desaturase activity was detected and showed a negative trend with an increase of salinity, and no significant differences were found among salinity groups (P > 0.05).
The increase of SFA at the expense of MUFA most likely resulted from the inhibition of the A-9 desaturase enzyme system that is responsible for SFA desaturation, converting SFA into MUFA [45].
Indeed, the chronic treatment with risperidone or paliperidone induced liver enzymes such as fatty acid desaturase 2 [17].
The selected genes include four encoding signaling proteins (FGFR3 encoding fibroblast growth factor receptor 3, EPHB2 encoding ephrin type-B receptor 2, GREM1 encoding gremlin 1, and IGFBP2 encoding insulin-like growth factor binding protein 2), two extracellular matrix genes (COL3A1 encoding collagen, type III, alpha 1, and TNC encoding cytotactin or tenascin-C), and two metabolic genes (ACBD7 encoding acyl-CoA-binding domain containing 7 and SCD encoding stearoyl-CoA desaturase).
The top down-regulated genes were Major urinary protein 4 (Mup4), Major urinary protein 2 (Mup2), Carbonic anhydrase III (Ca3), Adiponectin (Adipoq), TATA box binding protein (Tbp), Stearoyl-CoA desaturase 1 (Scd1), ELOVL family member 5, elongation of long chain fatty acids (ElvolS), and tubulin (Tubg2) (Table 4).
In those studies, sterculic oil was found to suppress the bodily enzyme stearoyl-CoA desaturase 1 (SCD1).

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