This testing either is a skin prick or blood test for the two main species of dust mites:
Dermatophagoides pteronyssinus and Dermatophagoides farina.
house-dust mite
Dermatophagoides pteronyssinus (DerP): components nDer p 1 and nDer p 2
Testing was carried out for groups of food allergens (cow's milk, eggs, flour, meat I and II, fruit I, II and III, vegetables I and II) and for groups of aeroallergens (grass pollen, weed pollen, tree pollen, house dust,
Dermatophagoides pteronyssinus, animal hair-fur, feathers, vegetable fibers, fabrics, fungi, bacteria) using dialyzed extracts of allergens in a solution of a mixture of 50% glycerol solution in buffered saline solution (allergens preparations for SPT; Institute of Immunology, Zagreb, Croatia).
The extracts of allergens used were the following: house dust mite group:
Dermatophagoides pteronyssinus, Dermatophagoides farinae; animal group: cat, dog; mold group: Alternaria, Cladosporium; wild grass pollen group: weed mix, mugwort, lambs quarter, nettle, English plantain; grass pollen group: meadow grass, grass mix (Stallergenes 689-coded mixture of 12 grass pollens), cereal mix (oat, wheat, barley, corn); tree pollens: cypress, olive, ash, pine; and foods: milk, egg, wheat, peanut, hazelnut, and fish.
Malathion was associated with increased skin-prick test sensitization to
Dermatophagoides pteronyssinus in an Ethiopian study (Yemaneberhan et al.
Objective: To investigate the sensitivity of allergic asthma (AA) patients to house dust mites (HDM) by conducting skin tests, measuring total and specific IgE antibodies to
Dermatophagoides pteronyssinus and D.
ILC2s as key players in the development of allergic rhinitis (AR) have been proved, however, the effect of subcutaneous immunotherapy (SCIT) with
dermatophagoides pteronyssinus extract (Der p-SCIT) on ILC2s in AR patients is not clear.
The STIH included a standard battery of aeroallergens (FDA Allergenic[R], Brazil):
Dermatophagoides pteronyssinus (Dp), Blomia tropicalis (Bt), German cockroach (Gc), American cockroach (Ap), dog epithelium (De), cat epithelium (Ce), pollen mix (Po), fungi mix (Fa), positive control (histamine, 10 mg/mL) and negative control (excipient, salt solution).
The
dermatophagoides pteronyssinus, is actually a tiny spider that feeds off flakes of skin, which is why it is found in bedding, carpets, soft furnishings and clothing.
House dust mite,
Dermatophagoides pteronyssinus increases expression of MCP-1, IL-6, and IL-8 in human monocytic THP-1 cells.
The Chinese Herbal Medicine Formula Sheng-Fei-Yu-Chuan-Tang Suppresses Th2 Responses and Increases IFN gamma in
Dermatophagoides pteronyssinus Induced Chronic Asthmatic Mice.
Perennial AR is typically caused by allergens within the home like dust mite species Dermatophagoides farinae and
Dermatophagoides pteronyssinus, pets, such as cats and dogs, and cockroaches in infested households.
