The juvenile four-striped mouse skin (Figures 1(b), 1(d) and 1(f)) had an even dermal-epidermal junction lacking dermal papillae
and epidermal ridges.
HD-OCT "en-face" mode at the epithelial junction provided the architectural appearance of rings of bright cells surrounding the dark dermal papillae
. With the "slice" mode, the epithelial junction could be distinguished if the border was relatively flat and not overly serrated.
Isolation of human hair follicles and dermal papillae
Hyperkeratosis with alternating orthokeratosis and parakeratosis forming a checkerboard pattern in the stratum corneum, focal or confluent hypergranulosis, follicular plugging with perifollicular parakeratosis forming a shoulder effect, thick suprapapillary plates, broad rete ridges, narrow dermal papillae
, and sparse superficial dermal lymphocytic perivascular infiltration are frequent findings (5).
The hair follicle, a type of epidermal appendage, is composed of dermal papillae
cells, epithelial cells of the root sheath, and the hair shaft (Sperling, 1991).
and elastic fibers are absent and blood vessels are mal-developed.
Connective structures composed of collagen known as dermal papillae
that lie in the skin's dermis become smaller and weaker as collagen levels decline.
Direct immunofluorescence of healthy skin will show a typical granular IgA deposition in the dermal papillae
; some lesions will show a linear deposition of granular IgA in the basement membrane zone.
To address this question, Fernandes and his colleagues performed a further study in 2004, indicating that dermal papillae
of hair and whisker follicles were niches for rodent SKPs .
Topical vitamin C resulted in a significant increase of the density of dermal papillae
from 4 weeks onward compared to its vehicle.
Moreover, functional stem cell units have been described throughout all layers of human skin: hair follicle bulge, interfollicular epidermis, dermal papillae
, and perivascular hypodermal adipose tissue.
Oliver, "The induction of hair follicle formation in the adult hooded rat by vibrissa dermal papillae
," Journal of Embryology and Experimental Morphology, vol.