Caption: Figure 1: Depigmented
patch with leukotrichia right inferolateral neck.
macules are rectangular, rhomboid, or irregular in shape and usually have a symmetrical distribution.
According to some authors, epidermal melanocytes are absent in depigmented
Caption: Figure 1: Hypopigmented and depigmented
areas on the (a) face, scalp, and (b) ears, highlighted on Wood's lamp examination.
Phenotypically, it is characterised by acquired depigmented
patches of skin resulting from the death of melanocytes.
Vitiligo is a common acquired, idiopathic pigmentary disorder characterized by progressive circumscribed depigmented
macules or patches that corresponds histologically with reduced or absent cutaneous melanocytes.
Most of the patients (170 patients--85%) were asymptomatic except for the depigmented
patches and 20 (10%) had pruritus, 6 (3%) had photosensitivity, 4 (2%) had burning sensation.
Fundus examination revealed multiple depigmented
chorioretinal lesions 1/2 to 3 DD in size located in the posterior pole suggestive of chorioretinal atrophic patches (Figure 1).
In my practice, we have used microneedling for atrophic scars, repigmentation of depigmented
scars and vitiligo, stimulation of hair regrowth in noninflammatory alopecias, and treatment of burn scars.
Two types of skin aging exist: intrinsic aging, which includes changes due to normal maturity and occurs almost in all individuals; and extrinsic aging, caused by the extrinsic factors such as ultraviolet light, smoking and other environmental pollutant(s).5 Clinical features of intrinsic aging include skin dryness, wrinkling, laxity, decreased elasticity, lentigines, seborrheic keratoses, skin fragility and thinning, ecchymosis, depigmented
hair, fine hair/vellus hair, diffuse hair loss and thin, brittle nails.6 The clinical features of extrinsic aging include skin dryness, wrinkling, laxity, decreased elasticity with elastosis, skin fragility and thinning, stellate pseudoscars, freckling, lentigines and seborrheic keratosis.6
Surface was dry and depigmented
focally with areas of ulceration and healing.
A 49-year-old male, truck driver by occupation, detected to be HIV positive 6 months back with CD4 count 546 cells/mm3, presented to dermatological outdoor with history of depigmented
, asymptomatic skin lesions over the face, trunk, both upper limbs since last 2 months.