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 (DNase) [de-ok″sĭ-ri″bo-nu´kle-ās]
an enzyme that catalyzes the hydrolysis (depolymerization) of deoxyribonucleic acid (DNA).
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

de·ox·y·ri·bo·nu·cle·ase (DNAse, DNAase, DNase),

Any enzyme (phosphodiesterase) hydrolyzing phosphodiester bonds in DNA.
See also: endonuclease, nuclease.
Farlex Partner Medical Dictionary © Farlex 2012


(dē-ŏk′sē-rī′bō-no͞o′klē-ās′, -āz′, -nyo͞o′-)
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.


A gene on chromosome 14q11.2 that encodes a major apurinic/apyrimidinic (AP) endoDNAase, which is involved in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents, and in the redox regulation of transcriptional factors.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


(DNase) (de-oks'ē-rī'bō-nū'klē-ās)
Any enzyme (phosphodiesterase) hydrolyzing phosphodiester bonds in DNA.
See also: endonuclease, nuclease
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


An enzyme that cuts DNA strands by breaking PHOSPHODIESTER BONDS.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

deoxyribonuclease (DNAse)

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Androgen Ablation Leads to an Upregulation and Intranuclear Accumulation of Deoxyribonuclease I in Rat Prostate Epithelial Cells Paralleling Their Apoptotic Elimination J.
Measurement of deoxyribonuclease I activity in human tissues and body fluids by a single radial enzyme-diffusion method.
An abrupt elevation of the serum deoxyribonuclease I (DNase I) activity in acute myocardial infarction [Abstract].
Human genetically polymorphic deoxyribonuclease: purification, characterization, and multiplicity of urine deoxyribonuclease I.
Human urine deoxyribonuclease II (DNase II) isozymes: a novel immuncaffinity purification, biochemical multiplicity, genetic heterogeneity, and broad distribution among tissues and body fluids.
[34.] Shastina BB (2004) Deoxyribonuclease sperm of the sea urchin.
[35.] Lazarus RA, Wagener JS (2007) Recombinant Human Deoxyribonuclease I".
[39.] Taper HS (2008) Altered deoxyribonuclease activity in cancer cells and its role in nontoxic adjuvant cancer therapy with mixed vitamins C and K3.

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