deletion

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deletion

 [de-le´shun]
in genetics, loss of genetic material from a chromosome.
 Examples of large-scale chromosomal deletions: A, terminal; B, interstitial. From Dorland's, 2000.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

de·le·tion

(dĕ-lē'shŭn),
In genetics, any spontaneous elimination of part of the normal genetic complement, whether cytogenetically visible (chromosomal deletion) or found by molecular techniques.
[L. deletio, destruction]
Farlex Partner Medical Dictionary © Farlex 2012

deletion

(dĭ-lē′shən)
n.
1. The act of deleting; removal by striking out.
2. Material, such as a word or passage, that has been removed from a body of written or printed matter.
3. Genetics The loss, as through mutation, of one or more nucleotides from a chromosome.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

de·le·tion

(dĕ-lē'shŭn)
genetics Any spontaneous elimination of part of the normal genetic complement, whether cytogenetically visible (chromosomal deletion) or inferred from phenotypic evidence (point deletion).
[L. deletio, destruction]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

deletion

In genetics, the removal of a segment of DNA with joining up of the cut ends. as in the loss of a segment of a chromosome. Deletion of a single BASE PAIR is one of the kinds of point mutation. Deletion of a base pair triplet (codon) will result in a protein with a missing amino acid.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Deletion

The absence of genetic material that is normally found in a chromosome. Often, the genetic material is missing due to an error in replication of an egg or sperm cell.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
DNA was extracted (QIAGEN DNA extraction Kit, Germany) from 200-uL of blood sample collected in ethylene diamine tetra acetic acid (K3-EDTA), and -[alpha]3.7 kb deletion was detected by amplifying the [alpha]-globin genes using forward and reverse primers (Integrated DNA Technologies, USA) in separate reactions.
Deletion of GSTM1 and GSTT1 did not show statistically significant association with adult ALL (p=0.86 and p=0.35 respectively).
Small fragment deletions and duplications are predominant in the Duchenne muscular dystrophy gene
The additional features (abnormal physical findings) in our patient have not been previously reported with deletion of the 11p15.4 region.
Monogenic diabetes MODY 2 was suspected (mutations in GCK explains most cases of monogenic causes of diabetes in Spain) and MLPA was performed in the patient and her parents, showing an heterozygous GCK gene deletion and wild type results, respectively.
The corpus callosum, a fiber bundle that connects the left and right sides of the brain, was abnormally shaped and thicker in the deletion carriers, compared to controls.
In our study, the common [alpha]-giobin gene cluster deletions (-[alpha]3.7, -[alpha]4.2,--MED and -[alpha]20.5) were investigated and -[alpha]20.5 deletion was not seen in our cases, while -[alpha]20.5 deletion was estimated to be about 13.6% in Qazvin province, 1.9 % in Gilan province and 1.5% in Mazandaran province (41-43).
(i) Feature (1) (deletion length): split-reads mapping reacts badly on overlong deletions.
Multiplex PCR would offer a cost-effective solution for the detection of [alpha]-globin gene deletions.
"They affect more base pairs in the human genome than any other type of variation." Duplications make up 4.4 percent of the genome, while deletions affect 2.77 percent.
Because of X-linked inheritance of the DMD gene, deletions are easily identified by conventional M-PCR method in male patients only.
Our sample consists of 113 additions and 47 deletions of U.S.