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a mutation that results from insertion or deletion of a single nucleotide into, or from, the normal DNA sequence; because the genetic code is read three nucleotides at a time, all nucleotide triplets distal to the mutation will be one step out of phase and misread, and hence translated as different amino acids.
Farlex Partner Medical Dictionary © Farlex 2012
deletion mutationa type of MUTATION in which genetic material is removed from chromosomes or other DNA molecules (see CHROMOSOMAL MUTATION, POINT MUTATION). The deletion can be as small as a single DNA base (which can cause a misreading of the base sequence during PROTEIN SYNTHESIS, see FRAMESHIFT) to a large tract of DNA containing many GENES.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005