Mutation in hPER2 has a notable association with advanced sleep phase syndrome, whereas some haplotypes of hPER3 have shown an association with
delayed sleep phase syndrome. These conditions arise because of the alterations into casein kinase I[epsilon] (CKI[epsilon]) phosphorylation of the target clock proteins, affecting morningness and eveningness.
Some have speculated that
delayed sleep phase syndrome (DSPS) and depression might share genetic susceptibility factors, but preliminary data from an ongoing study suggest this may not be the case, Dr.
`Sleep specialists call this
Delayed Sleep Phase Syndrome (DSPS).
He was diagnosed with
Delayed Sleep Phase Syndrome, which means his body doesn't know when it's time to rest.
Pathologic sleep conditions such as sleep apnea and
delayed sleep phase syndrome have their symptomatic onset in adolescence (11).
This condition, known as
delayed sleep phase syndrome (DSPS), often leads to abuse of caffeine and other stimulants upon waking and tranquilizers and alcohol in the nightly struggle to doze off.
Caused most often by shift work and jet lag, some people also routinely have difficulty going to bed before two or three AM and waking up in the morning on time (
delayed sleep phase syndrome).
Delayed sleep phase syndrome: pathophysiology and treatment options.
The study found evidence that the hormone does decrease sleep onset latency, but only for those with
delayed sleep phase syndrome. There was no evidence that melatonin increases sleep efficiency or is helpful in preventing or treating jet lag or shift-work disorder, said AHRQ Director Carolyn M.
Delayed sleep phase syndrome or night owls find themselves unable to fall asleep 8 hours before they want to get up, leaving them drowsy in the morning and alert in the evenings.
Of the 32 patients in the study, 28 were diagnosed with sleep onset insomnia, 5 had
delayed sleep phase syndrome, 4 had sleep-maintenance insomnia, and 2 had a sleep-wake cycle disruption.
H, 26, of Treorchy, Rhondda, has
Delayed Sleep Phase Syndrome.