Delayed hypersensitivity reactions

Delayed hypersensitivity reactions

Allergic reactions mediated by T cells that occur hours to days after exposure.
Mentioned in: Allergies
References in periodicals archive ?
None of those 20 patients were observed to have developed immediate or delayed hypersensitivity reactions, investigators reported.
Delayed hypersensitivity reactions are also possible, characterized by erythema, edema, itching, a change in the contour of the injected implant, and, occasionally, an indurated papule or inflamed dermal nodule, but they are very rare after HA application.
NSAIDs can also induce immunological (noncross-reactive) hypersensitivity reactions, including IgE-mediated single-NSAID-induced urticaria/angioedema or anaphylaxis (SNIUAA), and T cell-mediated single-NSAID-induced delayed hypersensitivity reactions (SNIDHR).
Delayed hypersensitivity reactions to subcutaneously injected heparin are relatively common and present as eczematous plaques at injection sites (Anders & Trautmann, 2013).
It is fundamental to allogeneic- and synergeneic-graft rejection, graft-versus-host reactions and the delayed hypersensitivity reactions [10,21].
(2), (3) For those with food allergies that are not IgE-mediated and associated with delayed hypersensitivity reactions, estimates are more difficult to determine.
We conducted a prospective study of 60 patients in a tertiary care referral center to ascertain the status of cell-mediated immunity as determined by delayed hypersensitivity reactions in patients with nasopharyngeal carcinoma (NPC) or allergic rhinitis.
Non-IgE-mediated inflammatory responses to food antigens that are driven by T cells and other immune cell types have been implicated in delayed hypersensitivity reactions affecting both babies and adults (1,4).
Therefore, IgG is critical for diagnosing delayed hypersensitivity reactions.
The immunopathogenesis of food allergies may be governed by more than one immunologic mechanism, including immediate manifestations mediated by IgE; inflammatory reactions caused by immune complexes, lectins, and superantigens; and delayed hypersensitivity reactions associated with specific T lymphocytes (Helm and Burks 2000).
Of the 38 eligible patients, 20 consented to oral rechallenge in clinic, and none of them developed immediate or delayed hypersensitivity reactions.
Aspartame, for instance, is metabolized to formaldehyde, which has been associated with type 4 delayed hypersensitivity reactions. There's also been suggestions that sucralose may have negative effects on the thymus and spleen, and possible associations with autoimmune disorders, Dr.

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