blue diaper syndrome

(redirected from Defective tryptophan absorption)

blue diaper syndrome

[MIM*211000]
a disorder of tryptophan absorption; excess unabsorbed tryptophan in the intestine is metabolized to indoles and indicans, which are absorbed and lead to excretion of indican in the urine, which is oxidized in the diaper to indigo; patients also have hypercalcemia and nephrocalcinosis.

blue di·a·per syn·drome

(blū dīă-pĕr sindrōm)
Disorder of tryptophan absorption; excess unabsorbed tryptophan in the intestine is metabolized to indoles and indicans, which are absorbed and lead to excretion of indican in the urine, which is oxidized in the diaper to indigo.

blue diaper syndrome

A rare autosomal recessive syndrome in which the amino acid tryptophan is not absorbed from the gastrointestinal tract.