septo-optic dysplasia

(redirected from De Morsier syndrome)

septo-optic dysplasia

A rare developmental disorder of the brain and eye in which the optic disk and septum pellucidum do not develop normally, resulting in blindness, hormonal deficiencies, learning disabilities, decreased muscular tone, and, occasionally, seizures.
Synonym: Morsier syndrome
See also: dysplasia
References in periodicals archive ?
Previously described in the literature is septooptic dysplasia (SOD), or de Morsier syndrome, which is diagnosed with two of the three following criteria: optic nerve hypoplasia, pituitary abnormalities, and midline brain defects, classically an absent septum pellucidum.