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A heterocyclic sulphonamide used to manage respiratory acidosis by inhibiting renal carbonic anhydrase, which increases renal excretion of Na+, K+, and bicarbonate, and reduces ammonia excretion. Acetazolamide is also used to reduce fluid retention in congestive heart failure, control secondary glaucoma and preoperatively in acute angle-closure glaucoma, and may be of use in seizures, especially absence seizures.
Effect Reduced serum pH; increased urine pH


Acetazolamide, see there.