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Pharmacologic class: Antiprotozoal

Therapeutic class: Anti-infective

Pregnancy risk category B


Impedes pyruvate:ferredoxin oxidoreductase enzyme-dependent electron transfer reaction, which is essential to anaerobic energy metabolism


Oral suspension: 100 mg/5 ml

Tablets: 500 mg

Indications and dosages

Diarrhea caused by Giardia lamblia or Cryptosporidium parvum

Adults and children ages 12 and older: 500 mg (tablet or 25 ml suspension) P.O. every 12 hours with food for 3 days

Children ages 4 to 11: 200 mg (10 ml suspension) P.O. every 12 hours with food for 3 days

Children ages 1 to 3: 100 mg (5 ml suspension) P.O. every 12 hours with food for 3 days


• Hypersensitivity to drug or its components


Use cautiously in:

• renal, hepatic, or biliary disease or dysfunction; immunodeficiency (including human immunodeficiency virus); diabetes mellitus (suspension)

• concurrent use of warfarin or other highly plasma protein-bound drugs

• elderly patients

• pregnant or breastfeeding patients

• children younger than age 11 (tablets) or age 1 (suspension).


• Give with food.

• Because a single tablet contains more nitazoxanide than recommended for pediatric dosing, don't give tablets to children younger than age 11.

• Keep suspension container tightly closed and shake well before each use. Suspension may be stored for 7 days; after that, discard unused portion.

Adverse reactions

CNS: headache

GI: nausea, vomiting, diarrhea, abdominal pain


Drug-drug. Warfarin and other highly plasma protein-bound drugs with narrow therapeutic index: competition for binding sites, resulting in increased nitazoxanide blood level and efficacy

Patient monitoring

• Monitor renal and liver function tests frequently in patients with renal, hepatic, or biliary dysfunction.

• Monitor blood glucose levels in diabetic patients taking oral suspension.

Patient teaching

• Instruct patient to take drug with food.

• Inform diabetic patient that oral suspension contains sucrose.

• As appropriate, review all other significant adverse reactions and interactions, especially those related to the drugs mentioned above.


an antiprotozoal agent used to treat diarrhea caused by Cryptosporidium parvum or Giardia lamblia.


A synthetic salicylamide derivative and antiprotozoal that is active against Cryptosporidium parvum or Giardia lamblia infection, and which appears to also have activity against hepatitis B and hepatitis C.


A thiazolide anti-infective drug used to treat diarrhoea caused by Cryptosporidium parvum , Giardia lamblia, Entamoeba histolytica , Blastocystis hominis , Clostridium difficile and rotavirus.
References in periodicals archive ?
Luxe House, a distributor of premium beauty products throughout the Gulf region and several other Middle East countries, had six brands under its banner at Quintessence: Tom Daxon, Nishane, Le Galion, Signature Fragrances, Teaology, and Simone Cosac.
He joins from the catalogue company Daxon and he is responsible for further expanding and improving First4Lawyers' intuitive claimant website www.
Kodi Daharsh, Jessica Dally, Morgan Dally, Dakote Davis, Jeremiah Davis, McKenzie Davis, Paige Davis, Zachary Dawes, Mallory Daxon, Edgar De Los Santos, Nolan Deam, Erica Delano, Jacob Dellinger, Amina Donahoe, Kailey Dudley, Laura Duffield, McKenzie Duncan, Alexis Eads, Sarah Eisel, Joshua Ellington, Jeronimo Enciso Canchola, Katelynd Estess, Katherine Estess, Mya Falk, Katherine Fjordbeck, Meagen Fonseca, Shanah Forgey, Cole Fowler, Kalvin Freese, Joshua Fronczak, Adria Fuentes, Jordyn Fuller, Katie Fuller, Tayler Fulton,
BRANDY FINE ANOTHER spirit-inspired cologne, Tom Daxon VSOP Eau de Parfum, PS105 for 50ml, opens elegantly with notes of cognac and bergamot, before making way for spices and a musky finish (www.
com BRANDY FINE Another spiritinspired cologne, Tom Daxon VSOP Eau de Parfum, PS105 for 50ml, opens elegantly with notes of cognac and bergamot before making way for spices and a musky finish.
Sir Apparel strives to contribute to the global clothing market with the big brand names it offers, such as John Jewis, Marks and Spencers, Debenhams, House of Fraser, Daxon, to name a few.
Its European brands include La Redoute, Daxon, Vertbaudet, Cyrillus, Ellos, Jotex, Daxon and Castaluna, whereas its US brands comprise BrylaneHome, OneStopPlus.
BELGIUM: Alice Et Maman, Bellerose, Blue Stores Lola Et Liza, Cassis, Fred and Ginger, Mdr Nv, Okaidi, Paprika, Premaman, Sogesma, Veritas / FRANCE: 3 Suisses, Agora Distribution, Armand Thiery, Auchan Centrale d'achats, Decathlon (B Twin, Domyos, Fouganza, Inesis, Kalenji, Domyos, Oxylane), Bande Originale, Berenice, Bizzbee, Blanche Porte, Cache Cache, Camaieu, Cevimod Devianne, Chanel, Chevignon, Crossways, Cyrillus, Damart, Dauphitex, Daxon Movitex, Descamps, Devernois, Devred, Dim, Dino E Lucia, Diramode Pimkie, Dutexdor, Eram, Etam Lingerie Sas, Eurodisney Sca, Galec, Grain De Malice, Groupe Beaumanoir, Groupe Etam, Groupe Zannier Kenzo/Jean Bourget, Groupe Zannier Decant Jullien, Groupe Zannier Absorba, Guy Laroche, Groupe Happychic, Jules, Id Group,
At the booths of its subsidiary Daxon Technology Inc.
The BenQ Group companies include BenQ Corporation, AU Optronics Corporation (world's top 3 manufacturer of large-size TFT-LCD panels), Qisda Corporation, Darfon Electronics Corporation, Daxon Technology Inc.
The Kiala service is available from over 150 companies, including the main mail order companies such as Bertelsmann (ECI, Home Shopping Service), Karstad Quelle Neckermann (Quelle, Neckermann, Peter Hahn), Klingel, Pinault Printemps Redoute (Le Redoute, Daxon, Edmee, Eveil & Jeux), Yves Rocher and so on.