reduction of the neutralizing effect of an antitoxin when toxin is mixed with it in divided portions, rather than adding the same total quantity of toxin in one step.
[Jean Danysz, Polish-born Fr. pathologist, 1860–1928]
A phenomenon that illustrates the reversibility of precipitation of antibody and antigen complexes. When a specified amount of diphtheria toxin is added all at once to an antitoxin serum, the mixture is nontoxic; but when the same quantity of toxin is added in portions at about 30-min intervals, the mixture is toxic.
Danysz,Jean, Polish pathologist in France, 1860-1928.
Danysz phenomenon - reduction of the neutralizing effect of an antitoxin when toxin is mixed with it in divided portions.