dang gui


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Related to dang gui: Angelica sinensis, Dang shen, Bai Shao

dong quai

(don kwi) ,

Angelica sinensis

(trade name),

Chinese Angelica

(trade name),

Dang Gui

(trade name),

Danggui

(trade name),

Don Quai

(trade name),

Ligustilides

(trade name),

Phytoestrogen

(trade name),

Radix angelicae gigantis

(trade name),

Tang Kuei

(trade name),

Tan Kue Bai Zhi

(trade name)

Classification

Therapeutic: none assigned
Premenstrual syndromeVarious uses as a blood purifierTopically in combination with other ingredients for premature ejaculation

Action

May have vasodilating and antispasmodic properties.
Binds to estrogen receptors.

Therapeutic effects

Improved ejaculatory latency.

Pharmacokinetics

Absorption: Unknown.
Distribution: Unknown.
Metabolism and Excretion: Unknown.
Half-life: Unknown.

Time/action profile

ROUTEONSETPEAKDURATION
POunknownunknownunknown

Contraindications/Precautions

Contraindicated in: Allergy to carrot, celery, mugwort or other members of the Apiaceae family; Obstetric: Pregnancy and lactation.
Use Cautiously in: Hormone sensitive cancers and conditions (may exacerbate effects or stimulate growth of cancer cells); Protein S deficiency (↑ risk for thrombosis); Surgery (discontinue 2 weeks prior to procedure).

Adverse Reactions/Side Effects

Dermatologic

  • photosensitivity

Gastrointestinal

  • diarrhea

Miscellaneous

  • Some constituents are carcinogenic and mutagenic

Interactions

Alcohol -containing preparations may interact with disulfiram and metronidazole.Use of dong quai with anticoagulant and antiplatelet drugs, thrombolytics, NSAIDs, some cephalosporins, and valproates may increase risk of bleeding. Herbs with antiplatelet or anticoagulant properties may increase bleeding risk when combined with dong quai including:angelica, clove, danshen, garlic, ginger, ginkgo, panax ginseng, and willow.
Oral (Adults) Bulk herb—3–4.5 g per day in divided doses with meals; Extract—1 ml (20–40 drops) three times daily.

Availability

Bulk herb: OTC
Extract: OTC

Nursing implications

Nursing assessment

  • Assess pain and menstrual patterns prior to and following menstrual cycle to determine effectiveness of this herbal supplement.
  • Assess for pregnancy prior to recommending use of the herbal supplement and warn women not to take this herb if pregnancy is planned or suspected.
  • Assess for history of hormone sensitive cancers or conditions and warn against use.
  • Assess medication profile including prescription and over the counter use of products such as aspirin and ibuprofen based products to treat menstrual pain.

Potential Nursing Diagnoses

Acute pain (Indications)
Deficient knowledge, related to medication regimen (Patient/Family Teaching)

Implementation

  • Take with meals.

Patient/Family Teaching

  • Warn patients not to take this medication if pregnant or breastfeeding.
  • Inform patients to avoid use of aspirin or other NSAIDs concurrently because of the risk of bleeding.
  • Notify patients that there are no studies supporting the use of this herbal supplement for treatment of menopausal symptoms.
  • Tell patients to consult their health care professional if taking prescription medications before taking Dong Quai.
  • Discontinue the herbal supplement if diarrhea or excessive bleeding occurs and contact a health care provider if symptoms do not resolve.
  • Instruct patients that photosensitivity may occur and to wear sun screen and protective clothing if sun exposure is anticipated.

Evaluation/Desired Outcomes

  • Reduction in menstrual pain and cramping and regular periods with normal flow.

dong quai

, dang gui (dŏng kwī) [Chinese]
An herbal remedy from the East Asian perennial herb Angelica sinensis, promoted for its palliative effects on the symptoms of menopause. Formal studies of the herb show that it is ineffective in relieving hot flashes.
References in periodicals archive ?
Dang gui and Huang qi are often prescribed together, the two herbs compose a formula, Dangguibuxue decoction, which is the most frequently used TCM formula with a function of tonifying qi and enriching blood [35, 36].
Based on our previous study, it has been reported that a CHM formula consisting of Jin yin hua, Huang qi, and Dang gui, named as Qiguiyin formula, can moderately downregulate the lymphocyte proliferation in rats with multidrug-resistant Pseudomonas aeruginosa infection and can increase the release of proinflammatory cytokines in early inflammatory response.
Radix et rhizoma ginseng (Ren shen), Poria (Fu ling) and Radix Angelicae Sinensis (Dang gui) were the most frequently used herbs in combination with licorice.
Chinese English name Botanical name Frequency name of herb Gan cao Licorice Clycyrrhiza 26,185 uralensis Dang gui Chinese Angelica Radix Angelicae 16,285 Sinensis Ren shen Panax Ginseng Radix et rhizoma 14,154 ginseng Fu ling Indian Bread Poria 13,624 Bai zhu Largehead Radix atractylodis 10,361 Atractylodes macrocephalae Rhizome Fang feng Divaricate Radix 8661 Saposhnikovia saposhnikoviae Root Mu xiang Aucklandia Lappa Radix aucklandiae 8212 Fu zi Monkshood Radix aconiti 8111 lateralis praeparata Huang qin Baical Radix Scutellariae 7903 Skullcap Root Huang lian Golden Thread Rhizoma coptidis 7504 Chinese Formulae Database contains 96,592 formulae records.
Licorice, dang gui, and blue cohosh showed clear evidence of binding to the estrogen receptor.
After adding extracts of dang gui to the animals' chow, however, the researchers discovered an increase in uterine weight.
The researchers plan to expose breast cancer cells to extracts of dang gui and some other herbal remedies.
In the Eagon study, only dang gui appeared to work like an estrogen in every test.
Guo uses this combination to treat constipation in cancer patients, it is because Dang Gui supplements the blood, while Zi Wan descends the qi.