danaparoid

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danaparoid

 [dah-nap´ah-roid]
an agent used as the sodium salt in prophylaxis of pulmonary thromboembolism and deep venous thrombosis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

danaparoid

Orgaran® Cardiovascular disease An injectable, LMW heparin that ↓ risk of postop DVT and PE after hip replacement surgery; it is also used for heparin-induced thrombocytopenia. See Deep vein thrombosis, Heparin-induced thrombocytopenia, Pulmonary embolism.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
A diagnosis of thrombophlebitis of the portal vein associated with CCF was made, and the patient was immediately managed with an intravenous broad-spectrum antibiotic (DRPM at 1.5 g/day) and anticoagulation therapy was started (danaparoid sodium at 2500IU/day).
Kasabach-Merritt syndrome associated with giant liver hemangioma; the effect of combined therapy with danaparoid sodium and tranexamic acid.
The team then decided to trial danaparoid sodium (Danaparoid), a low-molecular weight (LMW) heparin, chemically distinct from heparin.
Danaparoid sodium is an anticoagulant that inhibits activated factor X (factor Xa) or inhibits factor Xa and thrombin through antithrombin (Alving, 2003).
The home hemodialysis team drafted a danaparoid sodium administration procedure.
Two months later, in response to the patient reporting clotting in the venous chamber, the dosage of danaparoid sodium was increased to 2250 units/treatment.
However, as with danaparoid sodium, little is known about the utilization of argatroban in a home dialysis environment.
Pros and cons of danaparoid sodium Pro Con * Easily converted * Cost $18.78/each to NHD * Half-life is approximately eight hours * Anti Xa levels * No neutralizing agent stable post * Cross-reactivity with heparin hemodialysis * Re-occurrence of HIT Note: NHD = Nocturnal hemodialysis HIT = Heparin-induced thrombocytopenia Table Six.
Cost per treatment including staffing and supplies Nocturnal hemodialysis with heparin $103.85 Nocturnal hemodialysis with HDF $120.63 Nocturnal hemodialysis with citrate dialysate and HDF $127.37 Nocturnal hemodialysis with danaparoid sodium $141.41 Nocturnal hemodialysis with argatroban $420.52 Note: HDF = hemodiafiltration