DDB2(redirected from Damage-specific DNA-binding protein 2)
DDB2A gene on chromosome 11p12-p11 that encodes a protein necessary for the repair of UV-light-damaged DNA, which is the small subunit of DNA damage-binding protein (a heterodimer composed of a large (DDB1) and a small subunit) that functions in nucleotide-excision repair.
DDB2 mutations have been tentatively linked xeroderma pigmentosum complementation group E (XPE).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.