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Related to Dalmane: Halcion


trademark for a preparation of flurazepam hydrochloride, a sedative and hypnotic.

flurazepam hydrochloride

Apo-Flurazepam (CA), Bio-Flurazepam, Dalmane, Novo-Flupam (CA), PMS-Flurazepam (CA), Somnol (CA), Som Pam (CA)

Pharmacologic class: Benzodiazepine

Therapeutic class: Sedative-hypnotic

Controlled substance IV

Pregnancy risk category X


Depresses CNS at limbic, thalamic, and hypothalamic levels by enhancing inhibitory neurotransmitter effect of gamma-aminobutyric acid on neuronal excitability


Capsules: 15 mg, 30 mg

Indications and dosages

Short-term management of insomnia (less than 4 weeks)

Adults: 15 to 30 mg P.O. at bedtime

Dosage adjustment

• Elderly or debilitated patients


• Hypersensitivity to drug or other benzodiazepines

• Preexisting CNS depression

• Angle-closure glaucoma

• Pregnancy or breastfeeding


Use cautiously in:

• hepatic dysfunction

• history of suicide attempt or drug dependence

• elderly patients

• children younger than age 15 (safety not established).


• Before starting therapy, evaluate patient's mental status and check kidney and liver function tests and CBC.

Adverse reactions

CNS: dizziness, daytime drowsiness, headache, lethargy, confusion, poor concentration, depression, paradoxical excitation, ataxia

EENT: blurred vision

GI: nausea, vomiting, diarrhea, constipation, dyspepsia, abdominal pain

Respiratory: sleep apnea

Skin: rash

Other: abnormal taste, hangover, physical or psychological drug dependence, drug tolerance


Drug-drug. Antidepressants, antihistamines, opioids: additive CNS depression

Barbiturates, rifampin: increased flurazepam metabolism, decreased efficacy

Cimetidine, disulfiram, fluoxetine, hormonal contraceptives, isoniazid, ketoconazole, metoprolol, propoxyphene, propranolol, valproic acid: decreased flurazepam metabolism, enhanced efficacy

Levodopa: decreased levodopa efficacy

Theophylline: decreased sedative effects of flurazepam

Drug-diagnostic tests. Alanine aminotransferase, alkaline phosphatase, aspartate aminotransferase, total and direct bilirubin: increased levels

Drug-herbs. Chamomile, hops, kava, skullcap, valerian: additive CNS depression

Drug-behaviors. Alcohol use: additive CNS depression

Smoking: increased drug metabolism and clearance

Patient monitoring

• With long-term use, watch for signs and symptoms of physical or psychological dependence.

• Monitor patient's mental status, especially for depression and suicidal ideation.

• Watch for signs of drug hoarding or overuse.

• Monitor CBC and liver and kidney function tests.

Patient teaching

Urge patient (and significant other as appropriate) to report signs and symptoms of depression or suicidal thoughts or actions.

Advise female patient to immediately tell prescriber if she is pregnant. Caution her not to breastfeed.

• Inform patient that drug may cause physical or psychological dependence.

• Advise patient to minimize GI upset by eating frequent, small servings of food and drinking adequate fluids.

• As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the drugs, tests, herbs, and behaviors mentioned above.


a trademark for a benzodiazepine sedative-hypnotic (flurazepam hydrochloride).


See Flurazepam.


A brand name for FLURAZEPAM.
References in periodicals archive ?
Medicines such as Valium, Dalmane, diazepam and Zimovane are most commonly demanded.
I started taking a few Dalmane and Rohypnol when I was coming down off drugs.
The label change affects drugs including Zolpidem, marketed as Ambien/Ambien CR by Sanofi-Aventis; butabarbital, marketed as Butisol Sodium by Medpointe Pharmaceuticals HLC; flurazepam, marketed as Dalmane by Valeant Pharmaceuticals; quazepam, marketed as Doral by Questcor Pharmaceuticals; triazolam, marketed as Halcion by Pharmacia & Upjohn Inc.
Generic Trade Name Daily Dose Flurazepam Dalmane 15 mg Chlordiazepoxide Librium 20 mg Chlorazepate Tranxene 15 mg Prazepam Centrax 15 mg Diazepam Valium 5 mg Clonazepam Konopin 1.
In less than two days our undercover reporter assembled a massive haul of drugs including Prozac and heavy duty tranquillisers Xanax and Dalmane.
Each one contained a heavy duty drug - tranquillisers such as Dalmane or mood elevators such as Prozac - as well as a second, weaker medicine.
Our stash included Xanax, Prozac, Zimovane, Olanzapine, Dalmane and Lexapro.
The OBRA guideline for usage of these agents is that the use of any of these LABZs should be for no more than 10 consecutive days for sleep (although only Dalmane and Doral have FDA approval for sleep), or 4 consecutive months for anxiety or dementia UNLESS gradual dose reduction is attempted (not more than 10 to 15% of dose per week) and functional improvement is noted with use of the LABZ.
Phenobarbital Phenobarbital Multiple (multiple) Dalmane, Flurazepam HCl Roche Products Inc.
He made off with 20 boxes of Dalmane sleeping tablets.
Artane, Kemadrin, Benadryl, Atkineton, Parlodel, Permax, Eldepryl Antianxiety and Hypnotic Agents - Librium, Valium, Dalmane,
such as Valium, Dalmane, Centrax, Doral, ProSom, Librium,