DYNC1LI1

DYNC1LI1

A gene on chromosome 3p22.3 that encodes a cytoplasmic dynein complex protein which may play a role in retrograde intraflagellar transport and in cilia biogenesis. It is thought to act as a non-catalytic accessory component of the cytoplasmic dynein 1 complex, linking dynein to cargo molecules and to adapter proteins that regulate dynein function.
References in periodicals archive ?
We have also observed the downregulation of many genes involved in mitochondrial transport such as the family of dynactins (DCTN1, 2, 3, 5, and 6), dyneins (DYNC1H1, DYNC1I1, and DYNC1LI1), kinesins (KIF1B and KIF5C), and Miro (data not shown).