DUSP8

DUSP8

A gene on chromosome 11p15.5 that encodes dual-specificity phosphatase 8, a protein which is induced by nerve growth factor and insulin, inactivates SAPK/JNK and p38, and is expressed predominantly in the adult brain, heart and skeletal muscle.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Interestingly, the role of some of these enzymes, including MTMR1, mTmR2, DUSP7, DUSP8, DUSP23, STYXL1, and CDC25B, has not been studied in T cells.
DUSP5, DUSP6, DUSP8, and DUSP10 were found inside the group of middle expressed PTPs.
According to Liu et al., miR-21 promotes high-glucose-induced cardiac fibrosis though JAK/SAPK and p38 signaling pathway by suppression of dual specific phosphatase 8 (DUSP8) expression [58].