DTaP vaccine


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Related to DTaP vaccine: Hib vaccine

DTaP vaccine

A preparation of diphtheria and tetanus toxoids and acellular pertussis proteins. It is used to immunize children against all three infections or adults at high risk of complications of infection with pertussis.
See also: vaccine
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Data Source: Prospective cohort study involving 70 women and their infants; some of the mothers received DTaP vaccine during pregnancy.
The other candidate Tdap vaccine, Adacel, is nearly identical to Sanofi Pasteur's currently licensed DTaP vaccine, Daptacel, except that it contains lower levels of diphtheria toxoid and one of five pertussis antigens.
In fact, Aventis Pasteur has already received approval to produce a new DTaP vaccine, Daptacel, to complement our U.S.
Their case-control study showed that the protection provided by the DTaP vaccine was short-lived, such that each year after completing the fifth dose the likelihood of developing PCR-proven pertussis climbed by an average of 42% (N.
Klein and her colleagues performed a case-control study using information in the Kaiser Permanente database on 277 patients aged 4-12 years who had received the full series of the DTaP vaccine but had nevertheless tested positive for pertussis between 2006 and 2011.
Several studies have suggested that maternal pertussis antibodies can inhibit active pertussis-specific antibody production after administration of DTaP vaccine to infants of mothers vaccinated with Tdap during pregnancy, referred to as blunting (12,17).
In a pivotal clinical study of 4,114 healthy 10-18 year olds, Boostrix (tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine adsorbed [Tdap]) was comparable in both immunogenicity and safety with a currently licensed tetanus-diphtheria toxoid(Td) vaccine and produced antibody responses at least as high as those seen in infants who receive the current higher-antigen DTaP vaccine, said Dr.
It appears that switching DtaP vaccine brands midstream has no affect on the child's antibody development and their ultimate protection from these childhood diseases.
The odds of a child developing pertussis increase as the interval since he or she received the fifth and final dose of the DTaP vaccine increases, according to a report.
Kinrix is licensed for use as the fifth dose of the DTaP vaccine series and the fourth dose of the IPV series in children aged 4-6 years whose previous DTaP vaccine doses were DTaP (Infanrix, GlaxoSmithKline) and/or DTaP-Hepatitis B-IPV (Pediarix, GlaxoSmithKline) for the first 3 doses and DTaP (Infanrix) for the fourth dose (1,2).
In fact, Aventis Pasteur has already received approval to produce a new DTaP vaccine, Daptacel, at our Canadian facility to complement our U.S.
found that, compared with 4- to 10-year-olds who had received five doses of DTaP vaccine, the odds of receiving a pertussis diagnosis were nine times higher for unimmunized children, and the estimated vaccine effectiveness was 89% and was even higher in years 1, 2, and 3 after the fifth dose," he noted.