Primeau reported on seven children who had experienced
DT vaccine reactions, but who were subsequently skin tested and then vaccinated successfully with a meningococcal vaccine that is conjugated to diphtheria protein.
"
DT vaccine sensitivity can be lost over time," said Dr.
* Another manufacturer quit making diphtheria and tetanus toxoids for pediatric use, leaving only one manufacturer of
DT vaccine.
While most infants and children under 7 years of age should get the DTP, a few should delay getting this vaccine and a few others should get the
DT vaccine (diphtheria and tetanus vaccine) instead.
Infants were assigned randomly to be vaccinated with either DAPTACEL[TM], another investigational acellular pertussis vaccine, whole-cell pertussis DTP vaccine, or
DT vaccine as placebo at ages 2, 4, and 6 months.
Salman Rafique asked the EPI program officials to complete homework for the introduction of the following: Rubella, Hepatitis B birth dose, Diphtheria booster dose and
DT vaccines. Khawaja Salman also sought technical update on introduction of Cervical Cancer and asked to prepare detailed report on it.
[16] In a study in US, analysis confirmed a higher concentration of endotoxin in whole-cell DTP vaccines compared with DTaP or
DT vaccines as high concentrations of endotoxin may be correlated with a higher incidence of adverse events.
The Td vaccine contains about the same quantity of tetanus toxoid as the DTaP or pediatric
DT vaccines, but only one third to one eleventh as much diphtheria toxoid.
HbOC and PRP-T contain diphtheria or tetanus toxoid; therefore, children who have severe reactions to DTaP, DTP, or
DT vaccines may benefit from preferential use of PRP-OMP.