Primeau reported on seven children who had experienced DT vaccine
reactions, but who were subsequently skin tested and then vaccinated successfully with a meningococcal vaccine that is conjugated to diphtheria protein.
sensitivity can be lost over time," said Dr.
* Another manufacturer quit making diphtheria and tetanus toxoids for pediatric use, leaving only one manufacturer of DT vaccine
While most infants and children under 7 years of age should get the DTP, a few should delay getting this vaccine and a few others should get the DT vaccine
(diphtheria and tetanus vaccine) instead.
Infants were assigned randomly to be vaccinated with either DAPTACEL[TM], another investigational acellular pertussis vaccine, whole-cell pertussis DTP vaccine, or DT vaccine
as placebo at ages 2, 4, and 6 months.
Salman Rafique asked the EPI program officials to complete homework for the introduction of the following: Rubella, Hepatitis B birth dose, Diphtheria booster dose and DT vaccines
. Khawaja Salman also sought technical update on introduction of Cervical Cancer and asked to prepare detailed report on it.
 In a study in US, analysis confirmed a higher concentration of endotoxin in whole-cell DTP vaccines compared with DTaP or DT vaccines
as high concentrations of endotoxin may be correlated with a higher incidence of adverse events.
The Td vaccine contains about the same quantity of tetanus toxoid as the DTaP or pediatric DT vaccines
, but only one third to one eleventh as much diphtheria toxoid.
HbOC and PRP-T contain diphtheria or tetanus toxoid; therefore, children who have severe reactions to DTaP, DTP, or DT vaccines
may benefit from preferential use of PRP-OMP.