DRD2


Also found in: Acronyms.

DRD2

A gene on chromosome 11q23 that encodes G protein-coupled dopamine receptor D2, which inhibits adenylyl cyclase.

Molecular pathology
Defects in DRD2 are associated with myoclonic dystonia.
References in periodicals archive ?
Polymorphisms Taql A of the DRD2, Ball of the DRD3, exon III repeat of the DRD4, and 3' UTR VNTR of the DAT: association with childhood ADHD in male African-Caribbean cocaine dependents?
Interestingly, for the first time we also found that the activation in a part of the brain called the striatum was increased when those with the variant in FTO looked at high-calorie foods, but this depended on which variant of the other gene DRD2 they possessed.
Se ha sugerido tambien una asociacion del alelo Taql-B (BI) del gen DRD2 con el abuso de alcohol y drogas psicoestimulantes, como la cocaina o las anfetaminas (Noble 1998).
The DRD2 variant was 25 percent more common among those with a high pain perception compared to people with moderate pain.
DNA was extracted from blood using salting-out procedure [5] followed by amplification of DRD2 TaqI (rs1800497) flanking region using previously reported method [6].
Blum, who is credited with the first known association of the DRD2 with alcoholism and other addictive behaviors, hopes the GARS test will achieve two important outcomes.
Imaging gene-substance interactions: The effect of the DRD2 TaqIA polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward.
DRD2, DRD3 and DRD4 exert opposite effects and decrease cAMP production through inhibition of adenylyl cyclase activity.
Environmental Contingencies and Genetic Propensities: Social Capital, Educational Continuation, and Dopamine Receptor Gene DRD2.
Mothers who inherited either one or two copies of a particular form of the dopamine D2 receptor gene, dubbed DRD2, cited sharp rises in spanking, yelling and other aggressive parenting methods for six to seven months after the onset of the economic recession in December 2007, sociologist Dohoon Lee of New York University reported August 22.
DRD2 in the Striatum, for the gender effect and treatment effect, was the only significantly altered gene.