DRD2

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DRD2

A gene on chromosome 11q23 that encodes G protein-coupled dopamine receptor D2, which inhibits adenylyl cyclase.

Molecular pathology
Defects in DRD2 are associated with myoclonic dystonia.

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References in periodicals archive ?

Polymorphisms Taql A of the DRD2, Ball of the DRD3, exon III repeat of the DRD4, and 3' UTR VNTR of the DAT: association with childhood ADHD in male African-Caribbean cocaine dependents?

Developing treatments for stimulant abuse: a brief overview

Interestingly, for the first time we also found that the activation in a part of the brain called the striatum was increased when those with the variant in FTO looked at high-calorie foods, but this depended on which variant of the other gene DRD2 they possessed.

Research Links Genes to Heightened Brain Reward Responses to Foods High in Fat, Sugar

Se ha sugerido tambien una asociacion del alelo Taql-B (BI) del gen DRD2 con el abuso de alcohol y drogas psicoestimulantes, como la cocaina o las anfetaminas (Noble 1998).

Factores biologicos que predisponen la dependencia a sustancias psicoactivas estimulantes

between correctional attitudes and religion A gene X environment interaction Beaver KM, Gibson CL, Jennings between DRD2 and religiosity in the WG, Ward JT (33).

The role of religion in the promotion of health, in the prevention of violence and in the rehabilitation of individuals involved in criminal activity: literature review/O papel da religiao na promocao da saude, na prevencao da violencia e na reabilitacao de pessoas envolvidas com a criminalidade: revisao de literatura

The DRD2 variant was 25 percent more common among those with a high pain perception compared to people with moderate pain.

Scientists discover four genes

DNA was extracted from blood using salting-out procedure [5] followed by amplification of DRD2 TaqI (rs1800497) flanking region using previously reported method [6].

Association of dopamine receptor gene polymorphism and psychological personality traits in liability for opioid addiction

Blum, who is credited with the first known association of the DRD2 with alcoholism and other addictive behaviors, hopes the GARS test will achieve two important outcomes.

'Window into the brain of millions'

Imaging gene-substance interactions: The effect of the DRD2 TaqIA polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward.

Tentative evidence for striatal hyperactivity in adolescent cannabis-using boys: a cross-sectional multicenter fMRI study

DRD2, DRD3 and DRD4 exert opposite effects and decrease cAMP production through inhibition of adenylyl cyclase activity.

Associations between melanocortin, dopamine and serotonin neurotransmission and physical activity

Environmental Contingencies and Genetic Propensities: Social Capital, Educational Continuation, and Dopamine Receptor Gene DRD2.

Using fuzzy set qualitative comparative analysis (fs/QCA) to explore the relationship between medical "homeness" and quality

Mothers who inherited either one or two copies of a particular form of the dopamine D2 receptor gene, dubbed DRD2, cited sharp rises in spanking, yelling and other aggressive parenting methods for six to seven months after the onset of the economic recession in December 2007, sociologist Dohoon Lee of New York University reported August 22.

Recession alters parenting style: mothers with gene variant became more aggressive

DRD2 in the Striatum, for the gender effect and treatment effect, was the only significantly altered gene.