In our earlier study, we used the Reconstruct Programme for the geometric comparison of the DPED area .
Optical coherence tomography (OCT) was performed on the OCT Stratus (Zeiss, Jena, Germany) before evaluation to rule out cases of wet AMD and to confirm DPED. During the follow up, it was repeated every six months and whenever the occurrence of neovascular AMD or DPED was suspected.
DPED. The average DPED value at baseline in patients treated with rheohaemapheresis was 6.78[+ or -]3.79 [mm.sup.2]; after 3.5 yearsoffollowup,itdecreasedto4.13[+ or -]3.84[mm.sup.2] (P < 0.001).
Central retinal activity (mainly parafoveal activity between 1.8[degrees] and 7[degrees] of eccentricity or even paramacular activity between 5[degrees] and 13[degrees]) increased in the treated patients with an early decrease or complete disappearance of the DPED area.
In our study, the central retinal activity and BCVA increased in the treated patients with an early decrease or complete disappearance of the DPED area.
Initial results were presented in our previous study  in which we also demonstrated the influence of rheohaemapheresis on the reduction of size or disappearance of DPED. If the soft drusen progress into the DPED, which is the normal development of AMD, this pathological change gradually increases and shows no tendency for resorption.
From aircraft to sensor to network architecture, DPED
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