docusate calcium

(redirected from DOK)
Also found in: Acronyms.

docusate

 [dok´u-sāt]
any of a group of anionic surfactants widely used as emulsifying, wetting, and dispersing agents.
docusate calcium an ionic surfactant used as a stool softener.
docusate potassium an anionic surfactant used as a stool softener; administered orally.
docusate sodium an ionic surfactant used as a stool softener.

docusate calcium

Apo-Docusate Calcium (CA), Calax (CA), DC Softgels, Novo-Docusate Calcium (CA), PMS-Docusate Calcium (CA), Ratio-Docusate Calcium (CA), Soflax C (CA), Stool Softener DC, Surfak Liquigels

docusate sodium

Apo-Docusate Sodium (CA), Colace, Correctol, Correctol Stool Softener (CA), Diocto, Dioctyl (UK), Docusol (UK), Dom-Docusate Sodium (CA), D.O.S. Softgels, Docu-Soft, DOK, D-S-S, DulcoEase (UK), Dulcolax Stool Softener, Enemeez, Genasoft Softgels, Norgalax (UK), Novo Docusate (CA), PHL-Docusate Sodium (CA), PMS-Docusate Sodium, Ratio-Docusate Sodium (CA), Selax (CA), Silace

Pharmacologic class: Emollient

Therapeutic class: Stool softener, surfactant

Pregnancy risk category C

Action

Increases absorption of liquid into stool, resulting in softening of fecal mass. Also promotes electrolyte and water secretion into colon.

Availability

docusate calcium

Capsules: 240 mg

Capsules (soft gels): 240 mg

Rectal solution: 283 mg/5 ml

docusate sodium

Capsules: 50 mg, 100 mg, 250 mg

Capsules (soft gels): 100 mg, 250 mg

Liquid: 150 mg/15 ml

Syrup: 50 mg/15 ml, 60 mg/15 ml, 20 mg/5 ml, 100 mg/30 ml, 150 mg/15 ml

Tablets: 100 mg

Indications and dosages

Stool softener

Adults and children older than age 12: 240 mg (docusate calcium) or 50 to 200 mg (docusate sodium) P.O. daily until bowel movements are normal

Children ages 6 to 12: 40 to 120 mg (docusate sodium) P.O. daily

Children ages 3 to 6: 20 to 60 mg (docusate sodium) P.O. daily

Contraindications

• Hypersensitivity to drug

• Abdominal pain, nausea, or vomiting

• Intestinal obstruction

Precautions

Use cautiously in:

• pregnant or breastfeeding patients.

Administration

• Give tablets and capsules with full glass of water.

• Give liquid solution with milk or fruit juice.

• Be aware that excessive or long-term use may lead to laxative dependence.

Adverse reactions

EENT: throat irritation

GI: nausea, diarrhea, mild cramps

Skin: rash

Other: bitter taste, decreased appetite, laxative dependence

Interactions

Drug-drug. Mineral oil: increased mineral oil absorption, causing toxicity

Warfarin: decreased warfarin effects (with high doses)

Patient monitoring

• If diarrhea occurs, withhold drug and notify prescriber.

• Know that therapeutic efficacy usually becomes apparent 1 to 3 days after first dose.

Patient teaching

• Instruct patient to drink sufficient fluids with each dose and to increase fluid intake during the day.

• Advise patient to prevent constipation by increasing fluids and consuming more dietary fiber (as in fruits and bran).

• Inform patient that excessive or prolonged use may lead to laxative dependence.

• As appropriate, review all other significant adverse reactions and interactions, especially those related to the drugs mentioned above.

References in periodicals archive ?
We are faced with more questions than answers--and no matter how clever the search engines may be, this offers opportunities for DOK and other libraries.
The management at DOK believes it is of paramount importance to look beyond walls and borders in order to keep up with developments worldwide and thus to maintain its high level of service to the users.
DOK believes in a global library network that will help libraries maintain their important position in society and create a solid base for democracy.
Next, the reviewers read the definitions of DOK levels and were asked to think about typical behaviors for the grade level.
All reviewers were provided a description of the assessment system they were responsible for evaluating, DOK descriptions for the appropriate subject domain, and the two coding matrices.
DOK consistency reflects the extent to which the assessment items measure the range of expected knowledge.
Visitors can enjoy some of the games available in the DOK on platforms such as the Sony PlayStation, Nintendo Wii, as well as Mac or PC-based games.
Programmers at the DOK have also created their own automation system, finding that the products available lacked the ability to provide support for their more innovative approach to library functions.