DNMT


Also found in: Acronyms.

DNMT

This is the retired HUGO symbol for what is now designated DNMT1.
References in periodicals archive ?
DNMTs, for instance, represent a portion of one's internal environment, while toxins or toxic conditions represent the external environment.
And also, it will replace nucleoside during DNA proliferation which will disable DNMT and causes DNMTs degradation.
These DNAm modifications are then propagated during embryonic development to all somatic cell lineages (including precursors of peripheral blood cells) and maintained throughout life by the action of maintenance DNMTs, which copy these modifications from cell to cell during successive cell divisions (Davies et al.
acetaldehyde) can impact methylation patterns by altering DNMT activity.
At the same time, SAH levels increase, which inhibits DNMT.
Infusion of a DNMT inhibitor into the NAc of chronically stressed animals reduced these observed behaviors.
The NNK-induced DNMT proteins would bind with the tumor suppressor genes, inducing the overexpression of DNA methyltranferase 1.
Characteristics of the 90 women included in the analyses of DNMT gene expression [see Supplemental Material, Table 1 (http://dx.
Estrogen receptor genes are found to be silenced, or turned off, in human breast cancer cells and thus the reactivation of these genes using HDAC and DNMT inhibitors may provide insight in developing drug targets to treat breast cancer.
contextual fear conditioning) was shown to increase the expression of DNMT 3a and 3b, but not DNMT 1 in the adult hippocampus, whereas infusion of a DNMT inhibitor blocked memory formation (Miller and Sweatt 2007).
We found no significant associations between DNMT polymorphisms and As metabolism among the Argentinean women.
1 SGI-110, Astex Pharmaceuticals' Second Generation DNMT Inhibitor