genetic marker

(redirected from DNA marker)
Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to DNA marker: DNA ladder, Genetic markers

genetic

 [jĕ-net´ik]
1. pertaining to reproduction or to birth or origin.
2. inherited.
genetic code the arrangement of nucleotides in the polynucleotide chain of a chromosome; it governs the transmission of genetic information to proteins, i.e., determines the sequence of amino acids in the polypeptide chain making up each protein synthesized by the cell. Genetic information is coded in DNA by means of four bases: two purines (adenine and guanine) and two pyrimidines (thymine and cystosine). Each adjacent sequence of three bases (a codon) determines the insertion of a specific amino acid. In RNA, uracil replaces thymine.
genetic map
1. the location of mutations along the length of a chromosome, as determined by recombination experiments. The unit of length is the centimorgan (cM), one crossover per meiosis.
2. the sequence of base pairs along the DNA of a chromosome, a technique being applied to humans.
A gene map of Chromosome 18. From Copstead, 1996.
genetic marker a gene having alleles that are all expressed in the phenotype, that is, they are codominant, and which can be used to study inheritance. The various blood group systems and serum or red blood cell proteins easily detected by electrophoresis or immunodiffusion are commonly used markers.

ge·net·ic de·ter·mi·nant

any antigenic determinant or identifying characteristic, particularly those of allotypes.
Synonym(s): genetic marker

genetic marker

n.
A gene, DNA sequence, or gene product whose inheritance can be traced through a pedigree or phylogeny. Genetic markers are used in paternity testing, studies of evolution, and evaluating genetic contributions to phenotypes including disease. Genetic markers associated with certain diseases can often be detected in the blood serum, where their presence is used to determine whether a person is at high risk for developing a disease.

ge·net·ic de·ter·mi·nant

(jĕ-net'ik dĕ-tĕr'mi-nănt)
Any antigenic determinant or identifying characteristic, particularly those of allotypes.

genetic marker

A gene or DNA sequence that indicates the presence of a disease or a probable risk of developing it.

genetic marker

  1. a phenotypic character that can be assigned to a GENE to mark its position on the GENOME.
  2. a characteristic feature of the GENOTYPE, such as a NUCLEOTIDE signature, gene or HETEROCHROMATIC region, that can be used to track a particular individual, TISSUE, CELL, NUCLEUS, CHROMOSOME, PLASMID or gene. Genetic markers are used, for example, to detect the presence of cloning VECTORS in GENETIC ENGINEERING and to monitor ORGANISMS released into the environment. See RESTRICTION FRAGMENT LENGTH POLYMORPHISM.
References in periodicals archive ?
Genetic diversity and sex determination in date palms (Phoenix Dactylifera L.) based on DNA markers. Arab J.
Since the advent of PCR, nonamplifying null alleles at DNA markers have been reported in the American oyster, the Pacific oyster, and the geoduck clam (Hu & Foltz 1996, Launey & Hedgecock 1999, 2001, McGoldrick et al.
Identification of DNA Marker for Nectariless trait in Cotton using Random Amplified Polymorphic DNA technique.
Sappington's team is also using DNA markers to genetically locate the gene or genes responsible for "rotation resistance," an egg-laying behavior that enables some rootworm populations to survive rotations of corn with soybean, a nonhost crop on which the pest's caterpillars cannot feed.
Molecular weight markers (1kb and 100 bp DNA markers (BIONEER, Republic of Korea) were also run alongside the gel.
DNA marker applied to city manhole covers Well done Amey and the council, just tell the thieves to wear industrial chemical proof gloves.
Disc Graphics approach to making use of the DNA marker is simple.
Segregating markers were judged for deviations from the expected 1:1 (of AFLP marker and microsatellite DNA marker polymorphic in one parent) or 1:1:1:1 and 1:2:1 (of microsatellite DNA marker polymorphic in both parents) phenotypic ratios with chi-square testing.
We propose a new approach for the noninvasive prenatal detection ofT21 from maternal plasma that is based on measuring the ratio of the concentrations of a fetal-specific DNA-methylation marker on chromosome 21 and a fetal-specific DNA marker on a reference chromosome.
DNA marker technology has been extensively exploited in varietal improvement programmes during last few years (Legesse et al., 2007).
For a DNA marker to be considered as one to identify a species and to distinguish it from other species, it must be exclusive for the species as well as being monomorphic.