blunt end

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blunt end

In a health care institution, the administrative or bureaucratic apparatus that supports and often directs patient care. Individuals actually providing the care (aides, midlevel pesonnel, nurses, and physicians) are said to work at the “sharp end” of health care.
Medical Dictionary, © 2009 Farlex and Partners

blunt end

An ending in DNA in which both strands of the molecule stop at the same base-pair so that no single strand protrudes.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

blunt end

the terminus of a NUCLEIC ACID DUPLEX, in which the two strands of the MOLECULE are base-paired along their entire length, so that there is no overhanging 3'- or 5' END. It is sometimes called the FLUSH END. see DNA STRUCTURE, RESTRICTION ENZYME. Compare OVERHANGING END.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
(3-7) XLF is shown to stimulate the Lig4 activity toward incompatible or mismatched DNA ends. (1)
The arch-shaped Mre11 homodimer is assembled by interactions of two manganese-containing nuclease domains, which are each flanked by nuclease capping domains controlling active site access [158] (together comprising the phosphodiesterase domain) for DNA ends [161] and is then trailed by C-terminal Rad50-binding domains often not included in crystallographic structures.
Work over the last 10 years, pioneered in large part in the Faculty of Medicine 'n' Dentistry, revealed that the enzyme PNKP plays a critical role in the repair of broken DNA ends produced by radiation and other agents.
Second generation noninvasive fetal genome analysis reveals de novo mutations, single-base parental inheritance, and preferred DNA ends. Proc Natl Acad Sci 2016;113:E8159 -68.
Schellenberg explained that TOP2 normally conceals its cut DNA ends within the core of the TOP2 protein that encircles DNA.
Cleaved DNA ends were then re-united to each other either through non homologous recombination (NHR) or homologous recombination (HR)[13].
A cop says he has no idea how bodily fluid containing his DNA ended up on the body of a 14-year-old girl that he and four other men are accused of sexually assaulting.
Such breaks produce, at least transiently, free DNA ends, which are capable of strand invasion, initiating the process of recombination [70].
The majority of HR repair is mediated by Rad52 epistasis group that includes the Rad51, Rad52, Rad54, Rad55, Rad57, MRE11 and NBS1 function in the initial sensor of the broken DNA ends (Sonoda et al., 2001).
"If my brother's DNA ends up in the database, and he's forfeited his privacy rights by becoming a convicted felon," says Stephen Mercer, a Maryland Defense attorney, "has he also forfeited my privacy rights as a wholly innocent family member?"