DNMT3B(redirected from DNA MTase HsaIIIB)
DNMT3BA gene on chromosome 20q11.2 that encodes a DNA methyltransferase thought to function in de novo methylation, rather than maintenance methylation. The protein localises to the cytoplasm and nucleus; its expression is developmentally regulated.
DNMT3B mutations cause immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.