DNMT3B
(redirected from DNA (cytosine-5-)-methyltransferase 3 beta)DNMT3B
A gene on chromosome 20q11.2 that encodes a DNA methyltransferase thought to function in de novo methylation, rather than maintenance methylation. The protein localises to the cytoplasm and nucleus; its expression is developmentally regulated.Molecular pathology
DNMT3B mutations cause immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome.