DNMT1(redirected from DNA (cytosine-5)-methyltransferase 1)
DNMT1A gene on chromosome 19q13.2 that encodes a DNA (cytosine-5-)-methyltransferase 1, which methylates CpG residues and plays a critical role in establishing and regulating tissue-specific patterns of cytosine methylation.
Aberrant methylation patterns are associated with certain human tumours (e.g., breast carcinoma) and developmental
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