DMD


Also found in: Dictionary, Thesaurus, Financial, Acronyms, Encyclopedia, Wikipedia.

DMD

 
Doctor of Dental Medicine.

DMD

Abbreviation for Doctor of Dental Medicine; Duchenne muscular dystrophy.

DMD

abbr. Latin
Dentariae Medicinae Doctor (Doctor of Dental Medicine)

DMD

A gene on chromosome Xp21.2 that encodes dystrophin, a protein that anchors the extracellular matrix to the cytoskeleton via F-actin. It is the ligand for dystroglycan and a central component of the dystrophin-glycoprotein complex, which accumulates at the neuromuscular junction and at various synapses in the peripheral and central nervous systems and has a structural function in stabilising the sarcolemma. It plays a key role in signalling events and synaptic transmission. DMD is a highly complex gene, containing at least eight independent, tissue-specific promoters and two polyA-addition sites; it is the largest gene found in nature (2.4 Mb).

Molecular pathology
Defects of DMD cause both Duchenne- and Becker-type muscular dystrophy.

DMD

Abbrev. for Diploma in Dental Medicine.

Duchenne muscular dystrophy (DMD)

The most severe form of muscular dystrophy, DMD usually affects young boys and causes progressive muscle weakness, usually beginning in the legs.
Mentioned in: Muscular Dystrophy

DMD

Abbreviation for doctor of dental medicine.
References in periodicals archive ?
DMDs generally occur when aqueous humor enters the predescemetic space through a tear in the Descemet's membrane, which can happen during ocular surgeries through a corneal incision or blunt trauma to the eye.
Neither IL-1[alpha] nor IL-1[beta] immunoreactivity could be shown in a study investigating 8 DMD muscle samples [17], and the IL-1 family has been reported downregulated in DMD serum [31].
The knowledge of the allelic association and the determination of carriers is an important aspect in providing prenatal diagnosis and genetic counseling to DMD families17.
Edasalonexent (CAT-1004) is an investigational oral small molecule that is being developed as a potential therapy for all patients affected by DMD, regardless of their underlying mutation.
- There have been 20 licensing and asset acquisition deals involving DMD drugs during 2014-19, eight of which occurred in 2017.
When DMD flares up and I'm having a bad day with breathing and eating that gets me down.
"Through the expanded collaboration with CRISPR and the acquisition of Exonics, we are bringing together the intellectual property, technologies, and scientific expertise needed to establish a leading gene editing platform for DMD and DM1.
It was already known that DMD is caused by the body failing to produce the protein dystrophin, which is important for muscles to be able to function properly.
Pfizer and CYTOO will work together to develop and validate such a target discovery platform using a DMD patient muscle-derived MyoScreen platform.
Scientists for the first time have used CRISPR gene editing to halt the progression of Duchenne muscular dystrophy (DMD) in a large mammal, according to a study by UT Southwestern that provides a strong indication that a lifesaving treatment may be in the pipeline.
The UK's Medicines and Healthcare products Regulatory Agency (MHRA) has renewed the Early Access to Medicines Scheme (EAMS) scientific opinion for Santhera Pharmaceuticals' (SWX: SANN) Raxone (idebenone) for patients with Duchenne muscular dystrophy (DMD) in respiratory function decline who are not taking glucocorticoids, the company disclosed on Friday.
Background: Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are common X-linked recessive neuromuscular disorders caused by mutations in dystrophin gene.