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carbon monoxide diffusing capacity

A clinical test which provides an objective measure of lung function. It reflects the lung's ability to take up an inhaled nonreactive test gas—e.g., carbon monoxide (CO)—which binds to haemoglobin with such a high affinity that virtually all of the CO reaches the alveolar space. The CO crosses the alveolar air-blood barrier, reaching the red cells, binds to haemoglobin and is removed with the exhaled gas.


diffusion capacity of the lung.


diffusing capacity of the lung for carbon monoxide.
References in periodicals archive ?
Having had our diffusing capacity tested in a large number of pulmonary function laboratories, it is very alarming that we found that inter-laboratory DLCO results varied by up to 60% through out our State of California, in hospitals as well as in private physician offices.
Dermatomyositis patients with a mildly low DLCO (defined as 61%-75% of predicted) should also have a high-resolution chest CT, as well as echocardiography to rule out pulmonary hypertension.
The DLCO test is much more sensitive and is able to pick up the earliest signs of emphysema.
In multivariate regression models, 6MWT distance, self-report of being disabled, UCSD SOBQ total score, 6MWT Borg, age, and DLCO percent predicted were significant determinants of PCS score (model [R.
In ILD, these two parameters tend to decline in parallel, whereas in isolated PAH, the DLCO shows a disproportionate decline.
If no objective improvement (increased FVC or DLCO by > 10%) occurs within 6 to 9 months of starting therapy, the drug should be stopped and potentially changed to a different agent.
In all cases, final reports should include name references to the predicted sets used for specific tests (spirometry, lung volumes, DLCO, etc.
ndd's devices measure DLCO, FRC, LCI and FVC with their patented Ultrasonic TrueFlow(TM) technology, which requires no calibration and eliminates problems associated with traditional methods of flow measurement, making testing fast, reliable and error-free.