DLG7 | definition of DLG7 by Medical dictionary
DLGAP5 (redirected from DLG7)
DLGAP5 A gene on chromosome 14q22.3 that encodes disks-associated protein 5, a key regulator of adherens junction integrity and differentiation, which may be involved in CDH1-mediated adhesion and signalling in epithelial cells; it is a potential cell cycle regulator with a possible role in carcinogenesis.
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Other upregulated genes were related to cell proliferation and its control, such as cyclin-dependent kinase gene CDK1/CDC2; cyclin genes CCNA2, CCNB1, CCNB2, and CCNL2; the DLG7
component of the mitotic apparatus; the gene encoding the checkpoint kinase involved in response to DNA damage, CHEK1/CHK1; and BUB1 and MAD2L1, components of the spindle checkpoint.