(5) In our study, DLCO
is significantly lower in PLCH patients with a clinical diagnosis of PHT than PLCH patients without PHT, confirming similar results in previous studies.
All the patients of mean age 28.76667 years, were properly matched with no significant difference with respect to age, sex, height, weight, BMI, spirometric parameters (DLCO
) and baseline functional exercise capacity (6MWT), and baseline clinico-physiological parameters e.g.
Patients characteristics at inclusion in the study Male gender (%) 56 (18/32) Age (yrs) 68 [+ or -] 9 Current smoker (%) 37 (12/32) Previous smoker (%) 53 (17/32) Pack-year 37 [+ or -] 23 Body height (cm) 169 [+ or -] 8 Body weight (kg) 73 [+ or -] 15 FEVj (ml) 1851 [+ or -] 716 FEVj (% predicted) 71.5 [+ or -] 20.1 DLCO
(% predicted) 58.8 [+ or -] 19.2 PAPs (mmHg) 30 [+ or -] 5 Lesion size (mm) 16 [+ or -] 3 Lobar distribution of nodules at initial CT scan Right upper lobe 8 Middle lobe 1 Right lower lobe 8 Left upper lobe 7 Left lower lobe 8 Malignancy at the end of follow-up Lung adenocarcinoma 20 Squamous cell cancer 2 Small cell lung cancer 2 Metastatic carcinoma 1 Note: data are presented as frequencies or means [+ or -] SD.
Inversely, the present study showed that subjects with ACO shared the similar biological characteristics of asthma such as hypereosinophilia, increased total IgE, and high levels of FENO but also the functional characteristics of COPD such as distal airflow limitation, significant decreased DLCO
, and low levels of 6MWD and V[O.sub.2] max (Table 2).
No significant correlations between sCD163 levels and any clinical or laboratory variables could be found, including duration of the disease, mRSS, EScSG-AI score, FVC, DLCO
, CRP, or ESR.
is often mildly reduced and does not normalize following heart transplantation.
Caption: FIGURE 1: Spearman correlation of phase III slope of the nitrogen single-breath washout test ([SIII.sub.N2]) with A, hemoglobin (Hb) ([r.sub.s]=-0.344; P=0.034); B, forced vital capacity (FVC) ([r.sub.s]=-0.671; P< 0.0001); C, diffusing capacity for carbon monoxide (DLco
) ([r.sub.s]=-0.376; P=0.019); and D, the 6-min walking distance (6MWD) ([r.sub.s]=-0.554; P=0.0003).
Hence, This study was undertaken to assess whether petrol pump workers expose to air pollutants have changes in pulmonary function tests (PFTs) and to evaluate the diffusing capacity of lungs for carbon monoxide (DLCO
) and changes in hematological parameters such as hemoglobin (Hb) and packed cell volume (PCV) of the study group.
PFTs and carbon monoxide diffusion capacity (DLCO
) were measured with a Zan 100 (nSpire Health Inc., Oberthulba, Germany) PFT device.
Study subjects were adults aged 18-69 years with mean baseline modified Rodnan skin score of 30, mean baseline forced vital capacity of 74%, and mean diffusing capacity of the lung for carbon monoxide (DLCO
) of 53% of predicted.
Pulmonary function testing (PFT) revealed an FEV1/FVC ratio of 98% with diffusion capacity of carbon monoxide (DLCO