HDAC7

HDAC7

A gene on chromosome 12q13.1 that encodes histone deacetylase 7, which is responsible for deacetylating lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation tags epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.