Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.
Abbreviation for direct immunofluorescence.
Farlex Partner Medical Dictionary © Farlex 2012
TNFA gene on chromosome 6p21.3 that encodes a cytokine, primarily secreted by macrophages, which binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF can induce cell death of certain tumour cell lines, and it is a potent pyrogen causing fever either directly or by stimulating interleukin-1 secretion. It is implicated in the tumour-related cachexia. It may stimulate cell proliferation and induce cell differentiation.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.