DHEA-S

Also found in: Acronyms.

DHEA-S

A steroid secreted by the cortex of the suprarenal gland and the testis; a precursor of testosterone. Limited studies suggest that DHEA reduces the percentage of body fat, perhaps by blocking the storage of energy as fat. Commercial formulations of DHEA are marketed as dietary supplements, although it is neither a nutrient nor a component of the human food chain. It has been promoted for the prevention of degenerative diseases including atherosclerosis, Alzheimer dementia, and parkinsonism and other effects of aging, but none of the alleged benefits has been confirmed in large, randomized clinical trials. Long-term administration to postmenopausal women has been associated with insulin resistance, hypertension, and reduction of low-density lipoprotein cholesterol.

References in periodicals archive ?

Conclusion: The first-episode antipsychotic-naive schizophrenic patients showed a significantly higher blood level of DHEA-S compared with healthy controls.

Serum Levels of Neuroactive Steroids in First-episode Antipsychotic-naive Schizophrenic Patients and Its Correlation with Aggression: A Case-control Study

Numerous studies have established a clear connection between low DHEA-S levels and arterial narrowing and other characteristics of arterial walls.

DHEA reduces cardiovascular risks and promotes healthy longevity

5) indicates that linoleic acid, oleic acid, and DHEA-S are more significant than lysoPC, since more individuals in the control group are localized below the baseline, whereas the majority of patients are correctly assigned to the IPD group.

Fasting serum lipid and dehydroepiandrosterone sulfate as important metabolites for detecting isolated postchallenge diabetes: serum metabolomics via ultra-high-performance LC-MS

Previous smaller studies had found an association between low DHEA-S levels and heart and blood-vessel, or cardiovascular, disease, although their results were inconclusive.

Low steroid levels 'may up cardiovascular disease risk'

Aging is associated with a decrease in not only DHEA and DHEA-S but also in levels of follicle stimulating hormone (FSH), which stimulates the maturation of germ cells and regulates the development, growth, pubertal development and reproductive processes of the human body.

Hormone replacement and anti-aging

Yapilan korelasyon analizinde DHEA-S duzeyi ile hastalik suresi (r=-0.

The role of dehydroepiandrosterone sulfate in chronic idiopathic urticaria pathogenesis/Kronik idiopatik urtiker patogenezinde serum dehidroepiandrosteron sulfatin rolu

The product comes in two packages, Access DHEA-S Reagent packs (2x50 test) and calibrators (6 vials of 2mL/vial).

Beckman Coulter to Market New Reagent for Metabolic Disease Screening

Low DHEA-S in these women didn't appear to affect their sexual behavior, Dr.

Low DHEA-S levels, low libido strongly linked

Comment: This study showed that patients with AMD have significantly lower serum DHEA-S levels than matched controls.

Low DHEA levels associated with macular degeneration

However, the nocturnal rise for cortisol, androstenedione and DHEA appeared earlier, and the plasma levels of thyroid hormones, estradiol and DHEA-S were lower during the recovery experiment than in the control experiment.

Circadian rhythm of hormones is extinguished during prolonged physical stress, sleep and energy deficiency in young men

In the circulation, the predominant form is the largely inactive DHEA-S (5).

Plasma dehydroepiandrosterone and risk of myocardial infarction in women

Two large studies showed that levels of DHEA-S in elderly patients correlated significantly and positively with cognitive function.