DHEA-S


Also found in: Acronyms.

DHEA-S

A steroid secreted by the cortex of the suprarenal gland and the testis; a precursor of testosterone. Limited studies suggest that DHEA reduces the percentage of body fat, perhaps by blocking the storage of energy as fat. Commercial formulations of DHEA are marketed as dietary supplements, although it is neither a nutrient nor a component of the human food chain. It has been promoted for the prevention of degenerative diseases including atherosclerosis, Alzheimer dementia, and parkinsonism and other effects of aging, but none of the alleged benefits has been confirmed in large, randomized clinical trials. Long-term administration to postmenopausal women has been associated with insulin resistance, hypertension, and reduction of low-density lipoprotein cholesterol.
References in periodicals archive ?
Conclusion: The first-episode antipsychotic-naive schizophrenic patients showed a significantly higher blood level of DHEA-S compared with healthy controls.
Numerous studies have established a clear connection between low DHEA-S levels and arterial narrowing and other characteristics of arterial walls.
5) indicates that linoleic acid, oleic acid, and DHEA-S are more significant than lysoPC, since more individuals in the control group are localized below the baseline, whereas the majority of patients are correctly assigned to the IPD group.
Previous smaller studies had found an association between low DHEA-S levels and heart and blood-vessel, or cardiovascular, disease, although their results were inconclusive.
Aging is associated with a decrease in not only DHEA and DHEA-S but also in levels of follicle stimulating hormone (FSH), which stimulates the maturation of germ cells and regulates the development, growth, pubertal development and reproductive processes of the human body.
The product comes in two packages, Access DHEA-S Reagent packs (2x50 test) and calibrators (6 vials of 2mL/vial).
Low DHEA-S in these women didn't appear to affect their sexual behavior, Dr.
Comment: This study showed that patients with AMD have significantly lower serum DHEA-S levels than matched controls.
However, the nocturnal rise for cortisol, androstenedione and DHEA appeared earlier, and the plasma levels of thyroid hormones, estradiol and DHEA-S were lower during the recovery experiment than in the control experiment.
In the circulation, the predominant form is the largely inactive DHEA-S (5).
Two large studies showed that levels of DHEA-S in elderly patients correlated significantly and positively with cognitive function.