Lucky AW et al.23 in their study found that females with severe comedonal acne had significantly higher DHEA-S
and testosterone levels.
Biochemical measurements were performed in a qualified laboratory using the DHEA-s
, cortisol, and testosterone markers.
Results: Serum DHEA-S
level was significantly higher in the patient group (p = 0.001).
Total T, free T, androstenedione, DHEA-S
, hCG, T4, FT4, and T3 were all found to decline significantly after 2 weeks of HM evacuation.
The concentrations of specific metabolites were significantly higher in IPD and T2DM patients, compared with the control group, including linoleic acid, oleic acid, docosanoic acid, cholesteryl-[beta]-D-glucoside, and 1,2-distearoyl phosphatidyl serine, whereas other metabolites, such as lysophosphatidylcholine (lysoPC), lysophosphatidyl ethanolamine (lysoPE), DHEA-S
, and 5-hydroxykynurenine, were significantly lower in these groups.
Previous smaller studies had found an association between low DHEA-S
levels and heart and blood-vessel, or cardiovascular, disease, although their results were inconclusive.
is a kind of steroid hormone which serves as an indicator of adrenal cancer and Cushing's syndrome, as well as metabolic diseases.
In women under age 45, there was a very strong independent association of low desire, arousal, and responsiveness with low DHEA-S
levels, but no independent association with those sexual domains and testosterone levels.
At baseline, women with FSD had significantly decreased levels of testosterone and adrenal androgen precursors (dehydroepiandrosterone-sulfate or DHEA-S
) but not ovarian androgen precursors (androstenedione), compared with women with normal sexual function.
MALES FEMALE (Luteal Phase) Hormone (LabCorp) Units Approximate Median Value DHEA-S
pg/dL 347,400,000 271,600,000 Total Testosterone pg/dL 590,000 28,000 DHEA pg/dL 366,000 366,000 Pregnenolone pg/dL 100,000 100,000 Progesterone pg/dL 25,000 1,285,000 Total Estrogens pg/dL 7,750 25,300 Estrone (E1) pg/dL 4,200 8,200 Estradiol (E2) pg/dL 2,510 12,740 Free Testosterone pg/dL 1,790 210 As you can see, the level of DHEA-S
(the form of DHEA tested in male and female panels) exceeds all the other steroid hormones combined!