HAND2

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HAND2

A gene on chromosome 4q33 that encodes a DNA-binding basic helix-loop-helix (bHLH) transcription factor which plays an essential role in cardiac morphogenesis: it works in complement with HAND1 in the formation of the right ventricle and of the aortic arch arteries. HAND2 is required for vascular development and regulation of angiogenesis, possibly by a VEGF signalling pathway; it also plays a key role in limb development, particularly in the establishment of anterior-posterior polarisation, acting as an upstream regulator of sonic hedgehog (Shh) induction in the limb bud. It is involved in the development of branchial arches and head and neck structures. HAND2 dimerises with TCF3 gene products E12 and E47 and hairy-related transcription factors (HAND2, HEY1, HEY2 and HEYL), and it interacts with MDFIC. It is expressed in the heart.
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As Khan reached his hometown of Wazir Dhand in the Khyber district, relatives and neighbors gathered outside his house to greet him, placing garlands around his neck and showering him with prayers.
In Dadu district, minimum number of freshwater turtles was recorded from Kachri Dhand i.e.
The restaurateur said a number of waiters working in Wazir Dhand Food Street and Landi Kotal had lost job due to a slum in business.
The action was carried out in different areas of district Kohat including Jerma, Sur Gul, Qamar Dhand and Muslimabad areas.
Factory owner Sonu Dhand accused the Nepali father son-duo living in his factory of the theft.
The Swat's famous tourists destinations like Malam Jabba, Kalam, Madain, Fizagut and Mahu Dhand lake was being flooded with tourists these days and finding a suitable room in hotels, restaurants and rest houses for staying was merely a dream due to its nice and pleasant weather.
It is pertinent to mention here that the second power transformer of 132 KV Mardan Grid Station 2 got damaged last night,while one Power Transformers was already damaged during Eid Holidays .Now due to damaging of both the power transformers consumers of 11 KV Duranabad, New Bughdada.Malakand Road, Gari Kapora, Mall Road, Par Hoti,Shah Dhand, Jugan Nath, Bala Ghari,Zandu, Eid Ghah, Shan Kar, Kuju Khan and Carnal Jawad Babini and LTC feeders have been affected.
PANIC GRIPS PEOPLE: Panic gripped the residents of Shin Dhand area after a fighter jet crossed the sound barrier in early hours on Sunday.
Other dignitaries present on this occasion were Chhattisgarh Industries Minister Amar Agrawal, Chief Secretary Vivek Dhand, Additional Chief Secretary N.
Power supply will also remain suspended from 132 KV Mardan-2 Grid Station on August 16,17,22 and 23 from 8:00 A.M to 11:00 A.M resultantly consumers of 11KV Shah Dhand, Par Hoti, Doranabad, Malakand Road, Shankar, New Bughdada, Babini, New Eid Ghah, Bala Ghari, Lakson Tobacco Company, Jaganath, Guju Khan, Mall Road, Ghari Kapora, Zandu, Aziz Batti feeders will face inconvenience.
The force of the political administration established a check post in the area of Wazir Dhand area of Khyber Agency and after checking a Suzuki vehicle (N8421) driving by Bilal Khan son Liaquat Ali and recovered dozen of bottles of liquors form the car.